
Báo cáo khoa học: Formation of highly toxic soluble amyloid beta oligomers by the molecular chaperone prefoldin
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Alzheimer’s disease (AD) is a neurological disorder characterized by the presence of amyloidb(Ab) peptide fibrils and oligomers in the brain. It has been suggested that soluble Ab oligomers, rather than Ab fibrils, contribute to neurodegeneration and dementia due to their higher level of toxicity.
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