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Báo cáo khoa học: Knockdown of integrin b4-induced autophagic cell death associated with P53 in A549 lung adenocarcinoma cells
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Integrin b4 is a tissue-specific protein, but its role in autophagy of lung adenocarcinoma cells is not clear. In this study, we used microtubule-associated protein 1 light chain 3 processing and acridine orange staining to reveal that knockdown of integrin b4 by its specific siRNA induced autophagic cell death in A549 lung cancer cells.
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