Báo cáo khoa học: Major phosphorylation of SF1 on adjacent Ser-Pro motifs enhances interaction with U2AF65
35
lượt xem 4
download
lượt xem 4
download
Download
Vui lòng tải xuống để xem tài liệu đầy đủ
Protein phosphorylation ensures the accurate and controlled expression of the genome, for instance by regulating the activities of pre-mRNA splicing factors. Here we report that splicing factor 1 (SF1), which is involved in an early step of intronic sequence recognition, is highly phosphorylated in mam-malian cells on two serines within an SPSP motif at the junction between its U2AF 65 and RNA binding domains.
Chủ đề:
Bình luận(0) Đăng nhập để gửi bình luận!
CÓ THỂ BẠN MUỐN DOWNLOAD