![](images/graphics/blank.gif)
Báo cáo khoa học: Mechanism for transcriptional synergy between interferon regulatory factor (IRF)-3 and IRF-7 in activation of the interferon-b gene promoter
42
lượt xem 4
download
lượt xem 4
download
![](https://tailieu.vn/static/b2013az/templates/version1/default/images/down16x21.png)
Theinterferon-bpromoter has been studied extensively as a model system for combinatorial transcriptional regulation. Invirus-infectedcells the transcription factorsATF-2, c-Jun, interferon regulatory factor (IRF)-3, IRF-7andNF-jB, and the coactivators p300/CBP play critical roles in the activa-tion of this and other promoters. It remains unclear, how-ever, why most other combinations of AP-1, IRF and Rel proteins fail to activate theinterferon-bgene. Here we have explored how different IRFs may cooperate with other fac-tors to activate transcription....
Chủ đề:
Bình luận(0) Đăng nhập để gửi bình luận!
![](images/graphics/blank.gif)
CÓ THỂ BẠN MUỐN DOWNLOAD