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Báo cáo khóa học: Mechanisms of internalization and recycling of the chemokine receptor, CCR5

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:10

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CCR5 is a G protein-coupled receptor that binds several natural chemokines but it is alsoa coreceptor for the entryof M tropic strains of HIV-1 into cells. Levels of CCR5 on the cell surface are important for the rate ofHIV-1 infectionand are determined by a number of factors including the rates of CCR5 internalization and recycling. Here we investigated the involvement of the actin cytoskeleton in the control of ligand-induced internalization and recycling of CCR5.

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Nội dung Text: Báo cáo khóa học: Mechanisms of internalization and recycling of the chemokine receptor, CCR5

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