intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khóa học: Mutational and structural analysis of cobalt-containing nitrile hydratase on substrate and metal binding

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:10

27
lượt xem
2
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

Mutants of a cobalt-containing nitrile hydratase (NHase, EC 4.2.1.84) fromPseudonocardia thermophilaJCM 3095 involved in substrate binding, catalysis and formation of the active center were constructed, and their characteristics and crystal structures were investigated. As expected fromthe structure of the substrate binding pocket, the wild-type enzyme showed significantly lower KmandKi values for aromatic substrates and inhibitors, respectively, than alipha-ticones.

Chủ đề:
Lưu

Nội dung Text: Báo cáo khóa học: Mutational and structural analysis of cobalt-containing nitrile hydratase on substrate and metal binding

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
6=>0