intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khoa học: Small molecule regulation of Sir2 protein deacetylases

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:10

42
lượt xem
3
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

The Sir2 family of histone⁄protein deacetylases (sirtuins) is comprised of homologues found across all kingdoms of life. These enzymes catalyse a unique reaction in which NAD + and acetylated substrate are converted into deacetylated product, nicotinamide, and a novel metabolite O-acetyl ADP-ribose. Although the catalytic mechanism is well conserved across Sir2 family members, sirtuins display differential specificity toward acetyl-ated substrates, which translates into an expanding range of physiological functions. ...

Chủ đề:
Lưu

Nội dung Text: Báo cáo khoa học: Small molecule regulation of Sir2 protein deacetylases

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
2=>2