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Báo cáo khoa học: Submembraneous microtubule cytoskeleton: interaction of TRPP2 with the cell cytoskeleton
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TRPP2, also called polycystin-2, the gene product ofPKD2, is a membrane protein defective in 10–15% of cases of autosomal dominant polycystic kidney disease. Mutations in PKD2 are also associated with extrarenal dis-orders, such as hepatic cystogenesis and cardiovascular abnormalities.
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