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Báo cáo khoa học: The occurrence of riboflavin kinase and FAD synthetase ensures FAD synthesis in tobacco mitochondria and maintenance of cellular redox status
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Intact mitochondria isolated from Nicotiana tabacumcv. Bright Yellow 2 (TBY-2) cells can take up riboflavin via carrier-mediated systems that oper-ate at different concentration ranges and have different uptake efficiencies. Once inside mitochondria, riboflavin is converted into catalytically active cofactors, FMN and FAD, due to the existence of a mitochondrial ribofla-vin kinase (EC 2.7.1.26) and an FAD synthetase (EC 2.7.7.2).
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