Báo cáo khóa học: The unusual methanogenic seryl-tRNA synthetase recognizes tRNASer species from all three kingdoms of life
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The methanogenic archaeaMethanococcus jannaschiiand M. maripaludiscontain an atypical seryl-tRNA synthetase (SerRS), which recognizes eukaryotic and bacterial tRNAs Ser , in addition to the homologous tRNA Ser and tRNA Sec species.The relativeflexibility in tRNArecognition displayed by methanogenic SerRSs, shown by aminoacyla-tion and gel mobility shift assays, indicates the conservation of some serine determinants in all three domains. The complex of M. maripaludisSerRS with the homologues tRNA Ser was isolated by gel filtration chromatography....
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