intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khoa học: Thioredoxin Ch1 of Chlamydomonas reinhardtii displays an unusual resistance toward one-electron oxidation

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:7

38
lượt xem
4
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

To test thioredoxin resistance to oxidizing free radicals, we have studied the one-electron oxidation of wild-type thio-redoxin and of two forms with the point mutations D30A and W35A, using azide radicals generated byc-ray or pulse radiolysis. The oxidation patterns of wild-type thioredoxin and D30A are similar. In these forms, Trp35 is the primary target and is repaired by one-electron reduction; first by intramolecular electron transfer from tyrosine, and then fromother residues. Conversely, duringoxidationofW35A, Trp13 is poorly reactive. For all proteins, activity is con-served showing an unusual resistance toward oxidation....

Chủ đề:
Lưu

Nội dung Text: Báo cáo khoa học: Thioredoxin Ch1 of Chlamydomonas reinhardtii displays an unusual resistance toward one-electron oxidation

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
3=>0