Báo cáo khoa học: UXT interacts with the transcriptional repressor protein EVI1 and suppresses cell transformation
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The EVI1 transcriptional repressor is critical to the normal development of a variety of tissues and participates in the progression of acute myeloid leu-kaemias. The repressor domain (Rp) was used to screen an adult human kidney yeast two-hybrid library and a novel binding partner designated ubiquitously expressed transcript (UXT) was isolated.
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