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Báo cáo Y học: Coordinated action of protein tyrosine phosphatases in insulin signal transduction

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:10

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Insulin is the principal regulatory hormone involved in the tight regulation of fuel metabolism. In response to blood glucose levels, it is secreted by the b cells of the pancreas and exerts its effects by binding to cell surface receptors that are present on virtually all cell types and tissues. In humans, perturbations in insulin function and/or secretion lead to diabetes mellitus, a severe disorder primarily characterized by an inability to maintain blood glucose homeostasis. Furthermore, it is estimated that 90–95% of diabetic patients exhibit resistance to insulin action....

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Nội dung Text: Báo cáo Y học: Coordinated action of protein tyrosine phosphatases in insulin signal transduction

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