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Báo cáo Y học: Oxidation of propionate to pyruvate in Escherichia coli Involvement of methylcitrate dehydratase and aconitase

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:11

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The pathway of the oxidation of propionate to pyruvate in Escherichia coliinvolves five enzymes, only two of which, methylcitrate synthase and 2-methylisocitrate lyase, have been thoroughly characterized. Here we report that the isomerization of (2S,3S)-methylcitrate to (2R,3S)-2-methyl-isocitrate requires anovel enzyme,methylcitratedehydratase (PrpD), and the well-known enzyme, aconitase (AcnB), of the tricarboxylic acid cycle.

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Nội dung Text: Báo cáo Y học: Oxidation of propionate to pyruvate in Escherichia coli Involvement of methylcitrate dehydratase and aconitase

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