Báo cáo Y học: Studies into factors contributing to substrate specificity of membrane-bound 3-ketoacyl-CoA synthases
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We are interested in constructing a model for the substrate-bindingsiteof fattyacidelongase-13-ketoacylCoAsynthase (FAE1 KCS),the enzyme responsible forproductionof very long chain fatty acids of plant seed oils.Arabidopsis thaliana andBrassica napusFAE1 KCS enzymes are highly homo-logous but the seed oil content of these plants suggests that their substrate specificities differ with respect to acyl chain length.
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