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Báo cáo Y học: The reactivity of a-hydroxyhaem and verdohaem bound to haem oxygenase-1 to dioxygen and sodium dithionite
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Recently we have shown that ferrica-hydroxyhaem bound tohaemoxygenase-1 canbe converted to ferrous verdohaem by approximately an equimolar amount ofO2in the absence of exogenous electrons [Sakamoto,H.,Omata,Y.,Palmer, G.,and Noguchi, M. (1999)J. Biol. Chem.274,18196– 18200]. Contrary to those results,other studies have claimed that the conversion requires both O2andanelectron.
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