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Chapter 103. Polycythemia Vera and Other Myeloproliferative Diseases (Part 7)

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Table 103-4 Risk Stratification for Idiopathic Myelofibrosis A. Prognostic factorsa Hemoglobin 30,000/µL Number of prognostic factors Risk group Median survival (months) 0 Low 93 1–2 High 17 B. Prognostic factorsb Hemoglobin 1% Number of prognostic factors Risk group Median survival (months) 0–1 Low 99 2–3 High 21 C. factorsc Prognostic Median survival (months) Age 10 gm% Karyotype: Normal 180 Abnormal 72 Age 65 years Hemoglobin ≤10 gm% Karyotype: Normal 44 Abnormal 16 Age 65 years Hemoglobin 10 gm% Karyotype: Normal 70 Abnormal 78 a From B Dupriez et al. Blood 88:1013, 1996. b From F Cervantes et al. Br J Haematol 102:684, 1998. ...

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  1. Chapter 103. Polycythemia Vera and Other Myeloproliferative Diseases (Part 7) Table 103-4 Risk Stratification for Idiopathic Myelofibrosis A. Prognostic factorsa Hemoglobin 30,000/µL Number of prognostic Risk group Median survival factors (months)
  2. 0 Low 93 1–2 High 17 B. Prognostic factorsb Hemoglobin < 10 gm% Constitutional symptoms Blast cells > 1% Number of prognostic Risk group Median survival factors (months) 0–1 Low 99 2–3 High 21
  3. C. Prognostic Median survival factorsc (months) Age 65 years
  4. Hemoglobin ≤10 gm% Karyotype: Normal 44 Abnormal 16 Age >65 years Hemoglobin >10 gm% Karyotype: Normal 70 Abnormal 78 a From B Dupriez et al. Blood 88:1013, 1996. b From F Cervantes et al. Br J Haematol 102:684, 1998. c From JT Reilly et al. Br J Haematol 98:96, 1997.
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