Chemical and pharmacological evaluation of manglicolous lichen graphis ajarekarii Patw. & C. R. Kulk

The chemical examination of ethanolic extract of Manglicolous lichen Graphis ajarekarii (Ga-Et) resulted in isolation of three known metabolites i.e. chiodectonic acid (1), graphenone (2) and graphisquinone (3). All the isolates (1-3) and Ga-Et were screened against DPPH, superoxide free radicals and ferric ion reducing power assays, and six different cancer cell lines (MDA-MB-231, SW620, HeLa, FADU, A549, SKOV3) and one normal human cell line (NHME).