Cancer cell

A fragment-based approach has been applied to derive 2-(7-hydroxy-2-oxo-2H-chromen-4- yl)acetic acid 1 into 4 new coumarin derivatives 2a-d through amide bonds. The compounds were screened for their anticancer activity using MTT assay on MCF-7 and HepG2 cell lines.

10p viaburame 14-03-2025 0 0   Download

Garlic has been utilized since ancient times for both culinary and medicinal purposes. Recent research has identified selenium compounds in garlic, including γ-Glutamyl-Se-methylselenocysteine (GGMSC), leading to the hypothesis that GGMSC acts as a carrier for Se-methylselenocysteine (MSC). Experiments conducted on animals by researchers indicate that the effects of GGMSC in garlic and MSC on cancer cells in experimental models are equivalent. This finding suggests that garlic is a potential chemotherapeutic agent to enhance cancer treatment.

5p tuongmotranh 18-03-2025 3 1   Download

A benzothiazole ring plays an important role in pharmacological target diseases, including metabolic diseases, cancer, anti-inflammatory, neurodegeneration, viral diseases, bacterial infections, fibrosis, and thrombosis. Hydrazone-hydrazide derivatives are present in numerous biological molecules and play a significant role in medicine and pharmacology.

9p viaburame 14-03-2025 2 1   Download

Breast cancer is the most common malignancy and the second leading cause of death in women. While tamoxifen (TAM) remains to be a first-line agent for prevention and treatment of estrogenreceptor (ER) positive breast tumors, TAM resistance represents one of the biggest clinical challenges in breast cancer therapy.

9p vihyuga 04-03-2025 3 1   Download

This study aims to present a case of pneumonitis in a patient treated with concurrent chemoradiotherapy (cCRT) followed by durvalumab, focusing on the clinical manifestations, management strategies, and the implications for medical practice.

6p viyamanaka 06-02-2025 2 2   Download

Extended mediastinal with bilateral recurrent laryngeal nerves (RLNs) lymph node dissection (LND) is critical to curative surgery in the treatment of esophageal squamous cell carcinoma (ESCC). Some reports in Robotic transthoracic esophagectomy (RTE) have some advantages over Thoracoscopic esophagectomy (TE) in increasing the exposure and accuracy of mediastinal LND. However, published data was still limited.

9p viakimichi 17-01-2025 3 2   Download

Green tea consumption has been shown to exhibit cancer-preventive activities in preclinical studies. Polyphenon E (Poly E) is a green tea standardized extract. This study was undertaken to examine the antiproliferative effect and pro-oxidant activity of Poly E on PC3 prostate cancer cells.

5p viuchiha 06-01-2025 1 1   Download

Colorectal cancer (CRC) is one of the most common malignant cancers of the colon worldwide. Several novel approaches to cancer treatment have emerged, including gene therapy, targeted therapy, and adjuvant therapies.

7p viharuno 03-01-2025 5 2   Download

Studies on nanoparticle-protein interaction have also not been studied. This would give information on ratio influence on the structural alteration of EGCg in EGCg-AuNPs and its functionality in vivo. Herein, the optimisation of EGCg-AuNPs will be determined with a large pool of stoichiometric synthesises of gold and EGCg. These optimised EGCg-AuNPs would then be studied with bovine serum albumin (BSA) for protein interactions, binding and thermodynamics.

177p runthenight07 01-03-2023 12 3   Download

The objectives of the thesis: Determine the chemical composition of three soft coral species S. nanolobata, S. conferta, S. leptoclados collected in the central sea of Vietnam; đetecting active substances with cytotoxic activity in soft corals studied, orienting their application for biomedical and pharmacological studies.

26p closefriend09 16-11-2021 16 4   Download

The purpose of the thesis research: Synthesis of new complexes of platinum and rare-earth elements containing quinoline's derivatives that are resistant to cancer cells, high antimicrobial activity or good fluorescence.

27p tunelove 10-06-2021 23 4   Download

Objectives: Assessment of anti-human colon cancer cell (HT-29 cell) efficacy and activating apoptosis of MeV and MuV combination in vitro. Assessment of C cell tumor efficacy of MeV and MuV combination in nude mice xenograft models.

26p petsematary 02-06-2021 12 3   Download

Demonstrating the main chemical constituents of Anodendron paniculatum (Roxb.) A.DC. Structural determination of isolated compounds; evaluation of the cytotoxic activities of isolated compounds against human cancer cell lines.

25p nguathienthan12 23-05-2021 14 3   Download

The research objectives of the thesis: Isolate and determine the chemical structure of compounds from C. candicans and C. macrophylla species collected in Vietnam. Assessment of toxic activity on some cancer cell lines: liver (Hep-G2), lung (Lu-1) and breast (MCF-7) of isolated clean compounds. Researching the chemical composition of C. candicans and C. macrophylla essential oils

29p extraenglish 24-05-2021 19 4   Download

Objective: Study on synthesis of nano dendrimer PAMAM with anticancer drugs carboplatin (CAR) and oxaliplatin (OXA) to reduce the toxicity of the drug to normal cells and improve the effectiveness on cancer cell destruction by increasing solubility, increasing drug storage capacity, targeting drugs passively.

27p extraenglish 24-05-2021 23 4   Download

The objectives of the thesis: Research in the toxin/protein having bioactive isolated from Heterometrus laoticus (H. laoticus) scorpion and krait Bungarus fasciatus (B. fasciatus) snake venom.

32p extraenglish 24-05-2021 15 3   Download

The objectives of the thesis: Research in the toxin/protein having bioactive isolated from Heterometrus laoticus (H. laoticus) scorpion and krait Bungarus fasciatus (B. fasciatus) snake venom.

32p extraenglish 24-05-2021 23 3   Download

Isolate and determine the chemical structure of compounds from C. candicans and C. macrophylla species collected in Vietnam; assessment of toxic activity on some cancer cell lines: liver (Hep-G2), lung (Lu-1) and breast (MCF-7) of isolated clean compounds, researching the chemical composition of C. candicans and C. macrophylla essential oils.

29p capheviahe26 25-01-2021 37 3   Download

Assessed the level of mRNA expression of CIZ1b, VEGF, EGFR mutations and the rate of Merkel cell infection in patients with non-small cell lung cancer. Assessed the level of mRNA expression of CIZ1b, VEGF, EGFR mutations and the rate of Merkel cell infection in patients with non-small cell lung cancer.

32p trinhthamhodang7 31-08-2020 38 3   Download

Study the Malondialdehyde content in patients with colon cancer who underwent radical surgery treatment. Evaluate the changes in red blood cell Malondialdehyde content of patients with colon cancer after radical surgery.

30p angicungduoc6 21-07-2020 28 2   Download