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Design, synthesis, and biological evaluation of novel N4 -substituted sulfonamides: Acetamides derivatives as dihydrofolate reductase (DHFR) inhibitors

Chia sẻ: ViJiraiya2711 ViJiraiya2711 | Ngày: | Loại File: PDF | Số trang:18

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Sulfonamide derivatives are of great attention due to their wide spectrum of biological activities. Sulfonamides conjugated with acetamide fragments exhibit antimicrobial and anticancer activities.

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Nội dung Text: Design, synthesis, and biological evaluation of novel N4 -substituted sulfonamides: Acetamides derivatives as dihydrofolate reductase (DHFR) inhibitors

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