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Endocrine and metabolic complications in children and adolescents with Sickle Cell Disease: An Italian cohort study
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Children with Sickle Cell Disease (SCD) show endocrine complications and metabolic alterations. The physiopathology of these conditions is not completely understood: iron overload due to chronic transfusions, ischemic damage, and inflammatory state related to vaso-occlusive crises may be involved.
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