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Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells
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Mutations in myosin chaperones Unc45b and Hsp90aa1.1 as well as in the Unc45b-binding protein Smyd1b impair formation of myofibrils in skeletal muscle and lead to the accumulation of misfolded myosin.
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