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Low serum gastrin associated with ER+ breast cancer development via inactivation of CCKBR/ERK/P65 signaling
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Gastrin is an important gastrointestinal hormone produced primarily by G-cells in the antrum of the stomach. It normally regulates gastric acid secretion and is implicated in a number of human disease states, but how its function affects breast cancer (BC) development is not documented.
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