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Maximum-parsimony haplotype frequencies inference based on a joint constrained sparse representation of pooled DNA

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DNA pooling constitutes a cost effective alternative in genome wide association studies. In DNA pooling, equimolar amounts of DNA from different individuals are mixed into one sample and the frequency of each allele in each position is observed in a single genotype experiment.

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Nội dung Text: Maximum-parsimony haplotype frequencies inference based on a joint constrained sparse representation of pooled DNA

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