Nitric oxide synthase in the skeletal muscle and arterioles of rats with streptozotosin induced diabetes mellitus

Nitric oxide synthase (NOS) that uses NADPH as a cofactor is an enzyme which produces nitric oxide (NO) from L-arginine. Endothelial-derived (eNOS), inducible (iNOS) and neuronal (nNOS) nitric oxide synthase are 3 known isoforms.