Synthesis of alternating copolymer PAspNa-alt-PAsp(Pr) for drug delivery system

Alternating copolymers (ACs) contain two distinct monomeric unit types dispersed in alternating order of hydrophilic block and hydrophobic block. ACs have extensive and versatile applications in both academia and industry, especially in drug delivery systems (DDS) due to their unique physical and chemical properties. In the present research, poly(β-benzyl l-aspartate) (PBLA) was prepared by ring-opening polymerization of BLA-NCA. The result obtained from GPC showed that PBLA was successfully synthesized with narrow weight distribution Mw/Mn = 1.055. T