The antidepressant-like effects of an n-butanol fraction of Ocimum sanctum Linn. extract in unpredictable chronic mild stress-induced depression in mice

In the present work, we aimed to examine the antidepressant-like effect and the underlying mechanism of OS-B using a UCMS model of depression. Our results suggested that OS-B exhibits anti-depressive effects at least in part via noradrenergic, dopaminergic, and/or serotonergic systems.