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A Systems Approach
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In the pathogenesis of myeloproliferative neoplasms (MPN), inflammation plays an important role. However, it is unclear whether there is a causal link between inflammation and MPNs. We used a bidirectional, two-sample Mendelian randomization (MR) approach to investigate the causal relationship between systemic inflammatory cytokines and myeloproliferative neoplasms.
12p
vishanshan
27-06-2024
1
1
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Macroscopic vascular invasion (MVI) significantly impacts survival in patients with hepatocellular carcinoma (HCC), warranting systemic therapy over locoregional therapy. Despite novel approaches, HCC with MVI has a poor prognosis compared to early-to intermediate-stage HCC. This study aimed to evaluate the safety and efficacy of carbon-ion radiotherapy (C-ion RT) for HCC characterized by MVI.
9p
vishanshan
27-06-2024
2
1
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The present research was designated to investigate the potential of ZnONP nanocomposites as a cancer chemotherapeutic-based drug delivery system and to assess the anti-tumor and anti-inflammatory effectiveness of ZnONP nanocomposites combination with systemic chemotherapeutic drugs doxorubicin (DOX) and folic acid (FA) in Ehrlich ascites carcinoma (EAC) tumor cell line both in vitro and in vivo.
16p
vishanshan
27-06-2024
1
1
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This study aimed to describe the government program-based development of the Rational Pharmacotherapy Action Plan in Finland as a part of the undergoing major health and social service system reform, also covering the implementation of rational pharmacotherapy in the reformed system and processes.
16p
vishanshan
27-06-2024
1
1
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Part 1 of ebook "Managing complex construction projects: A systems approach" provides readers with contents including: Chapter 1 - Introduction; Chapter 2 - Project management system (Part I); Chapter 3 - Project management system (Part II); Chapter 4 - Project management system (Part III); Chapter 5 - Work management system;...
127p
mothoiphong
28-06-2024
1
1
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Part 2 of ebook "Managing complex construction projects: A systems approach" provides readers with contents including: Chapter 6 - Quality management system; Chapter 7 - Bringing it all together; Chapter 8 - Lessons learned from the field;...
118p
mothoiphong
28-06-2024
1
1
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There is a growing recognition of multidisciplinary practices as the most rational approach to providing better and more efficient healthcare services. Pharmacists are increasingly integrated into primary care teams, but there is no universal approach to implementing pharmacist services across healthcare settings.
11p
vishanshan
27-06-2024
2
1
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Patient-centred measurement (PCM) emphasizes a holistic approach wherein the voices of patients are reflected in the standardized use of patient-reported outcome and experience measures and are represented throughout the continuum of measurement activities. Given the challenges of routinely integrating patient self reports into clinical care decisions, the perspectives of all healthcare system stakeholders, especially patients, is necessary to advance the science of PCM.
13p
vishanshan
27-06-2024
1
1
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We employed a system dynamics approach to assess and predict the effect of the general practitioner service package (GPSP) and complementary incentive policies on the contract rate for 2015–2030. First, the GPSP is designed to address the unique needs of occupational populations, enhancing the attractiveness of GP contracting services, including three personalized service contents tailored to demand-side considerations.
12p
vishanshan
27-06-2024
1
1
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Men with breast cancer experience unique physical and emotional challenges. However, a thorough understanding of these experiences including the psychosocial effects and supportive care needs have received less attention. In some settings, men with breast cancer experience stigma within the healthcare system and their care needs are not prioritised.
50p
vikoch
27-06-2024
1
1
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In this study, the simultaneous determination of Co, Cd, Ni, Cu, and Pb was carried out as a color complex with 4-(2-pyridylazo) resorcinol in an aqueous solution under the assesting of machine learning. A partial least-squares multivariate linear regression and artificial neuron network for the analysis of mixtures of metals were developed. MATLAB is a powerful software machine learning program that was used to support matrix calculations and displays.
8p
visergeyne
18-06-2024
0
0
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This paper presents a control approach for the double inverted pendulum on a cart (DIPC) by combining Hierarchical Sliding Mode Control (HSMC) and Disturbance Observer (DOB). The proposed method utilizes HSMC to ensure balance in both the pendulum angles and a cart position, while the DOB accurately estimates the system's disturbance.
10p
visergeyne
18-06-2024
0
0
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Part 2 book "Physical assessment of the newborn - A comprehensive approach to the art of physical examination" includes content: Abdominal assessment; genitourinary assessment; musculoskeletal system assessment; neurologic assessment; behavioral assessment; assessment of the dysmorphic infant; pain assessment in the newborn; assessment of the newborn with antenatal exposure to drugs.
195p
dianmotminh03
17-06-2024
1
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The findings reveal a remarkable consistency: all three legal systems predominantly follow the fictitious doctrine when conceptualizing “juridical person” in their civil regulations, especially their Civil Codes. While variations exist due to ideological and historical contexts, this uniformity emphasizes the enduring influence of Soviet law and legal tradition on legislators’ approach to this concept across these nations.
13p
viambani
18-06-2024
2
1
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The research design was conducted using quantitative approaches. The major findings showed that the students’ proficiency in English did not satisfy the expectations of the stakeholders. Therefore, some practical solutions are given to improve the students’ level of use of English for tourism, including designing English tourism curriculum; building an e-learning system supports students’ self-studying; students’ opportunities to communicate in English, and the assessment processes; strengthen cooperation, learning and exchange with international enterprises.
14p
tonhiemm
07-06-2024
0
0
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In relational and object-oriented database systems, fuzzy or uncertain data will always be naturally present. However, these systems have many limitations for handling complex data types of fuzzy nature. Therefore, to represent and process fuzzy data, they need a flexible and efficient fuzzy query system. To solve this challenge, this paper proposes two different approaches to increase the flexibility of the fuzzy interrogation system.
17p
viamancio
04-06-2024
0
0
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Fundamental analysis for dummies is one of the most approachable texts to tackle this somewhat complex topic. Rather than bog you down with the nitty-gritty details that academics pull their hair over, I’ve attempted to lay out all the main topics and techniques you’ll need to apply fundamental analysis to a variety of business tasks. And while fundamental analysis is useful for anyone with an interest in business, appreciate the fact you are likely hoping to make some money from fundamental analysis.
387p
zizaybay1104
29-05-2024
2
2
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Cryptography is concerned with the conceptualization, definition, and construction of computing systems that address security concerns. The design of cryptographic systems must be based on firm foundations. This book presents a rigorous and systematic treatment of the foundational issues: defining cryptographic tasks and solving new cryptographic problems using existing tools. It focuses on the basic mathematical tools: computational difficulty (one-way functions), pseudorandomness, and zero-knowledge proofs.
393p
zizaybay1103
29-05-2024
3
2
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As in any multiauthored textbook penned by When I was first approached by the publisher of this volume, Martinus Nijhoff, Boston, I writers of diverse backgrounds and interests, explored the possibility of writing a personal Modern Stereotactic Neurosurgery to some monograph on contemporary stereotactic extent suffers from incompleteness. Future surgery. After a review of available literature, volumes no doubt will include many additions several aspects became apparent.
508p
vimeyers
29-05-2024
2
2
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This book reflects a broad spectrum of current opinions and progress in the surgical management of liver, pancreatic and biliary disease. The enormous advances in diagnostic imaging techniques and in interven tional, radiological and biliary approaches, the pathophysiological problems and their management manifest often as complications in the post-operative period, new techniques and the results of surgical approaches are all thorough ly documented.
436p
vimeyers
29-05-2024
4
2
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