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Aberrantly sustained
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Tumor cells exhibit enhanced metabolism of nutrients to satisfy the demand of sustained proliferation in vivo. Seminal reports have presented evidence that tryptophan (Trp) metabolic reprogramming induced by aberrant indoleamine 2,3-dioxygenases could promote tumor development in several cancer types. However, the underlying mechanism of Trp metabolism associated tumor progression is not fully understood.
11p
vimahuateng
26-11-2021
8
1
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Interleukin 6 (IL-6)-mediated signal transducers and activators of transcription 3 (STAT-3) phosphorylation (activation) is aberrantly sustained in cholangiocarcinoma cells resulting in enhanced myeloid cell leukemia 1 (Mcl-1) expression and resistance to apoptosis.
11p
vilisa271
22-09-2020
11
0
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Cassava (Manihot esculenta Crantz) which is commonly called tapioca reigns as a major source of food to the hungry millions especially of the developing countries across the globe. Cassava is considered as the future food crop as regards to its biological efficiency coupled with ability to sustain under changing climate especially during drought and to grow well in marginal soils. However he aberrant weather conditions in the present scenario create unavailability of good planting material for cassava cultivation.
5p
trinhthamhodang1212
06-04-2020
12
1
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