Acute graft versus host disease
-
Umbilical cord blood transplantation (UCBT) from unrelated donors is one of the successful treatments for acute leukemia in childhood. The most frequent side effect of UCBT is peri-engraftment syndrome (PES), which is directly associated with the greater prevalence of acute and chronic graft-versus-host-disease (aGvHD and cGvHD).
11p vileonardodavinci 23-12-2023 4 2 Download
-
Severe graft versus host disease (GVHD) is the main reason for non-relapse mortality following allogeneic hematopoietic cell transplantation (HCT). We investigated the serum protein profles of patients who had undergone HCT to identify predictive biomarkers of severe acute GVHD (aGVHD).
12p vialfrednobel 23-12-2023 5 3 Download
-
Graft versus host disease (GvHD) is a frequent complication of allogeneic stem cell transplantation (alloSCT), significantly increasing mortality. Previous imaging studies focused on the assessment of intestinal GvHD with contrast-enhanced MRI/CT or 18F-FDG-PET imaging alone. The objective of this retrospective study was to elucidate the diagnostic value of a combined 18F-FDG-PET-MRI protocol in patients with acute intestinal GvHD.
10p vimahuateng 26-11-2021 8 1 Download
-
In previous studies, we found that doxorubicin-conjugated antiCD137 mAb selectively killed CD137-expressing T cells in vitro. Therefore, in this work we tried to test the ability of this conjugate in vivo. C57lb/6 mice were induced with acute GVHD for further examination.
6p tamynhan8 04-11-2020 7 2 Download
-
Graft-versus-Host Disease (GvHD) causes significant morbidity and mortality in patients after allogeneic stem cell transplantation. Donor T-cells cause inflammation and tissue damage in GvHD target organs such as liver, gut and skin.
8p vimanila2711 25-06-2020 18 0 Download
-
Achievement of target blood concentrations of cyclosporine (CsA) early after transplantation is known to be highly effective for reducing the incidence of acute graft versus host disease (aGVHD).
6p viorochimaru2711 29-05-2020 8 0 Download
-
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) from a geno-identical matched sibling (MSD) is one of the most successful therapies in patients with non-malignant hematological disorders. This study included 273 patients with severe aplastic anemia (SAA), 152 patients with B-Thalassemia major (BTM), 31 patients with Fanconi’s anemia (FA), 20 patients with congenital immunodeficiency diseases (ID), and 13 patients with inherited metabolic disorders (IMD) allografted from a MSD. In SAA, the 8-year overall survival (OS) of the whole group patients was 74%.
10p trinhthamhodang1 16-11-2019 17 0 Download
-
The purposes of this study were(1)to describe the levels of anxiety and depressive symptoms in parents of children undergoing hematopoietic stem cell transplantation(HSCT)before(Time 1[T1])and one month after transplantation(Time 2[T2]), and(2)to identify the pre-HSCT factors that predict anxiety and depressive symptoms in fathers and mothers one month after transplantation
11p viconandoyle2711 03-09-2019 30 0 Download
-
Severe graft-versus-host disease (GvHD) is a life-threatening complication after allogeneic hematopoietic stem cell transplantation (HSCT). Bone marrow mesenchymal stem cells (BM-MSCs) display immunosuppressive activity and have been previously shown to improve the outcome of GvHD therapy.
8p sony2711 28-01-2019 36 1 Download
-
Back or flank pain is a critical symptom that indicates a retrograde infection to kidneys, risk factor for which is graft versus host disease. Furthermore, adenovirus-induced nephritis is a high risk factor for disseminated adenovirus infection including symptomatic adenoviremia (Bruno et al., 2004). Clinical presentation of adenoviremia is low to high grade fever refractory to antibiotic or antifungal agents followed by multiple organ failure including acute renal failure which presents oliguria, elevation of serum creatinine and enlarged kidneys with hypo-density in CT scan.
148p ti_du_hoang 27-08-2012 59 4 Download
-
Graft-versus-Host Disease GVHD is the result of allogeneic T cells that were either transferred with the donor's stem cell inoculum or develop from it, reacting with antigenic targets on host cells. GVHD developing within the first 3 months posttransplant is termed acute GVHD, while GVHD developing or persisting beyond 3 months posttransplant is termed chronic GVHD.
5p thanhongan 07-12-2010 69 2 Download