Adult stem cells

Uveal melanoma (UVM) is the most common primary intraocular tumor in adults, with a median survival of 4–5 months following metastasis. DNA damage response (DDR) upregulation in UVM, which could be linked to its frequent activation of the PI3K/AKT pathway, contributes to its treatment resistance.

11p vishanshan 27-06-2024 0 0   Download

Ebook "Stem cells & regenerative medicine: From molecular embryology to tissue engineering" is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications.

632p ladongphongthanh1008 22-04-2024 4 3   Download

Ebook "Adult stem cells (Second edition)" takes a critical look at issues concerning the developmental or differentiation potential for a variety of tissue types and for specific adult stem cell types. Since the first edition appeared a decade ago, our understanding of adult stem cells, and more specifically tissue-specific adult stem cells, has advanced tremendously. And an increased interest in regenerative medicine and potential stem cell applications has driven a quest for better understanding of stem cell biology.

433p ladongphongthanh1008 22-04-2024 2 1   Download

Ebook "Endogenous stem cell-based brain remodeling in mammals" highlights the endogenous regenerative potential of the central nervous system in neonates and juveniles and discusses possible ways it might be manipulated for medical purposes. The first section provides a descriptive summary of the salient steps of human brain development with a discussion of comparisons with other mammalian brains. It also provides a historical perspective on our understanding of ongoing brain development throughout the lifespan and serve to introduce the concept of brain plasticity following injury.

234p ladongphongthanh1008 22-04-2024 3 2   Download

Ebook "Adult stem cell therapies: Alternatives to plasticity" explores various techniques for tissue and organ regeneration using stem cells isolated from adult tissues. It discusses alternative explanations of stem cell plasticity as well as current clinical results with adult stem cell therapies. It examines the presence of potential pluripotent stem cells in adult tissues, paracrine effects of stem cell therapies, and involvement of exosomes and microparticles into observed phenomena.

271p ladongphongthanh1008 22-04-2024 8 2   Download

Ebook "Neural stem cells in development, adulthood and disease" is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disease, mood regulation, and spinal cord regeneration, among others.

219p ladongphongthanh1008 22-04-2024 1 1   Download

Ebook "Regenerative biology of the eye" is a comprehensive look at the current knowledge on stem cell application for vision loss, showcasing different types of stem cells (adult, embryonic, iPSCs) for diseases of the front and the back of the eye. It also highlights data obtained in various models from fish to human, as well as from the bionic eye project for vision regeneration.

310p tracanhphuonghoa1007 22-04-2024 2 2   Download

Ebook "Adult stem cells: Biology and methods of analysis" offers readers a historical perspective as well as unique insights into cutting-edge thoughts. The volume contextualizes the recent discovery of stem/progenitor cell populations resident in many adult tissues and organs. It confronts the complexities scientists face in trying to validate these cells, while it also describes and critically evaluates the methods currently used to assess stem cell self-renewal.

282p tracanhphuonghoa1007 22-04-2024 4 2   Download

Ebook "The cell biology of stem cells" deals with multiple aspects of stem cell biology, ranging from their basic molecular characteristics to the in vivo stem cell trafficking of adult stem cells and the adult stem-cell niche, and ends with a visit to regeneration and cell fate reprogramming.

246p tracanhphuonghoa1007 22-04-2024 2 2   Download

Somatic genetic testing is rapidly becoming the standard of care in many adult and pediatric cancers. Previously, the standard approach was single-gene or focused multigene testing, but many centers have moved towards broad-based next-generation sequencing (NGS) panels.

14p vibransone 28-03-2024 4 2   Download

In numbers of healthy individuals are undergoing predispositional personal genome sequencing. Here we describe the design and early outcomes of the PeopleSeq Consortium, a multi-cohort collaboration of predispositional genome sequencing projects, which is examining the medical, behavioral, and economic outcomes of returning genomic sequencing information to healthy individuals.

13p vibransone 28-03-2024 2 1   Download

DNA methylation changes that accrue in the stem cell pool of an adult tissue in line with the cumulative number of cell divisions may contribute to the observed variation in cancer risk among tissues and individuals. Thus, the construction of epigenetic “mitotic” clocks that can measure the lifetime number of stem cell divisions is of paramount interest.

17p vibransone 28-03-2024 3 2   Download

Ebook "Applications of cell immobilisation biotechnology" consists of 33 chapters that are arranged into 5 parts: (1) “Tissue engineering”, (2) “Microencapsulation for disease treatment”, (3) “Food and beverage applications”, (4) “Industrial biochemical production”, and (5) “Environmental and agricultural applications”. In each part various related topics are presented in detail.

556p manmanthanhla0201 27-02-2024 3 2   Download

This article presents a case study of two white male siblings of 24 and 31 years of age of self-reported Ukrainian ethnicity diagnosed with adrenomyeloneuropathy (AMN) associated with a novel splice site mutation in the ABCD1 gene.

8p vitiki 30-01-2024 5 2   Download

Ebook "Stem cells, human embryos and ethics: Interdisciplinary perspectives" is written for several audiences: a) scholars and professionals working with stem cell research or with the ethical questions arising from this field (people from biology, medicine, law, philosophy, theology etc.), b) advanced and graduate students within the same professional disciplines and c) politicians and the general public interested in the burning ethical problems which are intensively debated in many countries.

258p tachieuhoa 28-01-2024 3 2   Download

Ebook "Stem cells in the respiratory system" focuses on reviewing the most relevant—and recent—ideas on using local, endogenous, and exogenous progenitor/stem cells in preventing and treating injury to the lung. The lungs are one of the most complex organs in the human body, with a mature adult lung boasting at least 40 morphologically differentiated cell lineages.

175p tachieuhoa 28-01-2024 6 2   Download

Ebook "Lipidomics of stem cells" combines the current knowledge on the role of lipids in stem cell pluripotency and differentiation. It showcases various approaches to the study of lipids and focuses on various types of stem cells and specific lipids driving maintenance or differentiation. The volume includes chapters reviewing roles of specific lipids in pluripotency, neurogenesis and exocytosis as well as in cancer stem cells.

217p lamquandat 28-12-2023 3 2   Download

Ebook "Adult stem cells: Methods and protocols" contains a collection of protocols from some of the major laboratories involved in stem cell research across the world. The research discussed in this book covers topics such as: isolating, characterizing and expanding dental pulp stem cells; manipulating the proliferative potential of cardiomyocytes by gene transfer; isolation of stromal stem cells from adipose tissue; noninvasive assessment of cell fat and biology in transplanted mesenchymal stem cells; and cell-free therapy for organ repair.

320p lamquandat 28-12-2023 5 2   Download

There is paucity of data regarding outcomes of children, adolescents and young adults (CAYA) patients with non-Hodgkin lymphoma (NHL) undergoing autologous stem cell transplantation (ASCT).

8p vileonardodavinci 23-12-2023 2 2   Download

The neural stem/precursor cells (NSCs) in the ventricular-subventricular zone (V-SVZ) contribute to adult neurogenesis and gliogenesis, however, the mechanisms regulating NSC phenotype and functions remain to be elucidated.

7p visoros 01-11-2023 6 1   Download