Advanced gastric cancer

To evaluate the efficacy and safety of TS1-Cisplatin regimen in the first - line treatment of metastatic gastric cancer patients. Methods: 38 eligible patients were treated with TS1-cisplatin at Hanoi Medical University Hospital from January 2018 to December 2021.

5p vinatisu 29-08-2024 2 0   Download

To investigate the difference between doublet and triplet neoadjuvant chemotherapy (NAC) regimens in efficacy and safety profile. Methods: A total of 227 locally advanced gastric cancer (LAGC) patients who received NAC and sequential radical gastrectomy were reviewed. After propensity score matching (PSM), 140 patients with similar baseline characteristics were selected.

11p vielonmusk 21-01-2022 10 2   Download

Advanced gastric cancer (AGC) is a disease with poor prognosis due to the current lack of effective therapeutic strategies. Immune checkpoint blockade treatments have shown effect responses in patient subgroups but biomarkers remain challenging. Traditional classifcation of gastric cancer (GC) is based on genomic profiling and molecular features.

13p vielonmusk 21-01-2022 10 1   Download

Survival times differ among patients with advanced gastric carcinoma. A precise and universal prognostic evaluation strategy has not yet been established. The current study aimed to construct a prognostic scoring model for mortality risk stratification in patients with advanced gastric carcinoma.

13p vielonmusk 21-01-2022 14 1   Download

Although nivolumab (anti-programmed cell death-1 antibody) is a promising approach for advanced gastric cancer (AGC), the response rate remains limited. The aim of this multicenter retrospective study was to determine if clinical features could serve as prognostic factors of the efficacy of nivolumab in patients with AGC.

12p vielonmusk 21-01-2022 18 0   Download

Safety and efficacy of immune checkpoint inhibitors in advanced gastric or gastroesophageal junction (GEJ) cancer could be demonstrated in predominantly Asian cohorts, whereas data in Western patients outside of clinical trials are vastly missing.

10p vielonmusk 21-01-2022 16 0   Download

Methylglyoxal is the most important intracellular glycation agent, formed nonenzymatically from triose phosphates during glycolysis in eukaryotic cells. Methylglyoxal-derived advanced glycation end-products are involved in neurodegenerative disorders (Alzheimer’s, Parkinson’s and familial amy-loidotic polyneurophathy) and in the clinical complications of diabetes.

11p fptmusic 12-04-2013 43 2   Download

Ribosomes position their substrate at stereochemistry suitable for peptide bond formation, and promote substrate-mediated cata-lysis. The linkage between substrate orientation, dominated by remote interactions, and a sizable symmetrical region identified in all known ribosome structures indicates a guided rotatory motion of aminoacylated-tRNAs along a ribosomal path leadings to the advance of nascent peptides into the protein exit tunnel at an extended conformation.

4p fptmusic 11-04-2013 24 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Upper abdominal body shape is the risk factor for postoperative pancreatic fistula after splenectomy for advanced gastric cancer: A retrospective study

7p matuot_238 13-10-2011 44 2   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Late-onset peritoneal recurrence of advanced gastric cancer 20 years after primary resection

4p matuot_238 12-10-2011 47 7   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Combination therapy with docetaxel and S-1 as a first-line treatment in patients with advanced or recurrent gastric cancer: a retrospective analysis

7p matuot_238 12-10-2011 67 6   Download