Animals and human

Humans and animals have formed powerful bonds across cultures and throughout history, in real life and in storytelling. Forming relationships with animals has been a fundamental part of the human experience around the globe and literature is filled with descriptions and imaginings of human and animal interaction. Human animal relationships appear in a wide range of literary genres, and the nature of the bonds formed between human and animal characters in literature is intriguingly diverse.

309p runthenight07 01-03-2023 6 3   Download

This Master by Research project aims to develop the human gas capsule that enables realtime intestinal gas profiling in a low-cost, non-invasive and accurate manner. The safety, viability, reliability and repeatability of the capsule will be evaluated in both laboratorial environments and animal trials that are influenced by dietary effect, heat-stress-induced gut disorder and dietary supplemental therapeutic agent.

104p runthenight04 02-02-2023 8 3   Download

This search resulted in the development of a practical software tool based on animated Venn diagrams (Dvenn) that attempted to exploit the inherent human ability to perceive quantities visually, a faculty described herein as visual numeracy. The exploitation of this faculty is considered here to be a valuable aid for group understanding of business presentation data. The development of the tool was an essential part of the research that was undertaken and the resulting software forms a significant portion of this practise based research.

237p runthenight04 02-02-2023 6 1   Download

Research objectives: Use the blended learning model in teaching to improve teaching efficiency and improve the online self-study capacity of human and animal physiology for biology pedagogy students.

27p thebadguys 08-06-2021 22 4   Download

Quantifying the multiple processes which control and modulate the extent of oral bioavailability for drug candidates is critical to accurate projection of human pharmacokinetics (PK). Understanding how gut wall metabolism and hepatic elimination factor into first-pass clearance of drugs has improved enormously. Typically, the cytochrome P450s, uridine 5′- diphosphate-glucuronosyltransferases and sulfotransferases, are the main enzyme classes responsible for drug metabolism. Knowledge of the isoforms functionally expressed within organs of first-pass clearance, their anatomical topology (e.

16p caothientrangnguyen 09-05-2020 19 1   Download

Research objectives: Systematize theories on human resources (HR) development, MR development in enterprises; Study the content of MR development and analyze the major factors affecting MR development in the SMEs of animal feed production industry in Vietnam; Recommend solutions to develop MR to meet the development needs of Vietnam animal feed production industry to 2020.

0p nguyenthiminh32 12-07-2014 60 5   Download

Trypanosoma brucei is the cause of the diseases known as sleeping sickness in humans (T. brucei ssp. gambiense and ssp. rhodesiense) and ngana in domestic animals (T. brucei brucei) in Africa. Procyclic trypomastigotes, the tsetse vector stage, express a surface-bound trans-sialidase that transfers sialic acid to the glycosylphosphatidylinositol anchor of procyclin, a surface glycoprotein covering the parasite surface. Trans-sialidase is a unique enzyme expressed by a few trypanosomatids that allows them to scavenge sialic acid from sialylated compounds present in the infected host. ...

10p system191 01-06-2013 44 4   Download

important regulators of biological processes in animals and plants. MiRNAs regulate gene expression at the posttranscriptional level by binding to mRNAs and either inhibit translation or modify the stability of the mRNA. Due to the important biological role of miRNAs it is of great interest to study their expression level in the cells. Furthermore, miRNAs have been associated with cancer and other diseases [1] and miRNA expression can help in the diagnosis and prognostic of human disease [2,3].

11p zingzing09 24-04-2013 51 3   Download

Intrinsic factor (IF) is the gastric protein that promotes the intestinal uptake of vitamin B12 . Gastric IF from animal sources is used in diagnostic tests and in vitamin pills. However, administration of animal IF to humans becomes disadvantageous because of possible pathogenic transmis-sion and contamination by other B12binders. We tested the use of recombinant plants for large-scale production of pathogen-free human recombinant IF. Human IF was successfully expressed in the recombinant plantArabidopsis thaliana....

6p tumor12 20-04-2013 37 3   Download

Tocopherols are essential micronutrients in human and animal nutrition due to their function as lipophilic anti-oxidants. Theyare exclusively synthesizedbyphotosynthetic organisms including higher plants. Despite the attributed beneficial health effects and many industrial applications, research on the tocopherol biosynthetic pathway and its regulation inplants is still limited.

9p tumor12 20-04-2013 40 4   Download

Transmissible spongiform encephalopathies (TSE) are fatal neuro-degenerative diseases of humans and animals. The underlying infectious agent, the prion, accumulates not only in the central ner-vous system (CNS) but also in secondary lymphoid organs. I will revisit the role of the immune system in peripheral prion pathogen-esis, while focusing on the mechanisms by which extraneural and extralymphatic prion infectivity develops.

64p fptmusic 11-04-2013 36 4   Download

Protein aggregation is central to most neurodegenerative diseases, as shown by familial case studies and by animal models. A modified ‘amyloid cas-cade’ hypothesis for Alzheimer’s disease states that prefibrillar oligomers, also called amyloid-b-derived diffusible ligands or globular oligomers, are the responsible toxic agent. It has been proposed that these oligomeric spe-cies, as shown for amyloid-b, b2 -microglobulin or prion fragments, exert toxicity by forming pores in membranes, initiating a cascade of detrimental events for the cell. ...

10p awards 06-04-2013 40 3   Download

The conduction of protons through human Nox2 has pre-viously been shown to be dependent upon His115. Align-ment of sequences for both animal and plant Nox proteins indicated that histidines 115 and 119 are both highly con-served, while His111 was conserved among animal homo-logues of Nox1–4. To investigate the possible role that these histidine residues might play in the conduction of protons through Nox2, we have introduced both paired and single mutations into these histidine residues.

8p awards 05-04-2013 43 4   Download

Aryl acid adenylation domains are the initial enzymes for aryl-capping of catecholic siderophores in a plethora of microorganisms. In order to over-come the problem of iron acquisition in host organisms, siderophore bio-synthesis is decisive for virulence development in numerous important human and animal pathogens.

11p dell39 27-03-2013 29 3   Download

A pair of nuclear receptors, ecdysone receptor (EcR) and ultraspiracle (USP), heterodimerize and transduce ecdysteroid signals. The EcR and its nonsteroidal ligands are being developed for regulation of transgene expres-sion in humans, animals and plants. In mammalian cells, EcR:USP heterodimers can function in the absence of ligand, but EcR⁄retinoid X receptor (EcR:RXR) heterodimers require the presence of ligand for activa-tion.

12p dell39 27-03-2013 43 4   Download

The last step of the biosynthesis ofl-ascorbic acid (vitamin C) in plants and animals is catalyzed by l-gulono-1,4-lactone oxidoreductases, which use bothl-gulono-1,4-lactone and l-galactono-1,4-lactone as substrates. l-Gul-ono-1,4-lactone oxidase is missing in scurvy-prone, vitamin C-deficient ani-mals, such as humans and guinea pigs, which are also highly susceptible to tuberculosis.

11p inspiron33 25-03-2013 52 4   Download

Melatonin is a ubiquitous molecule and widely distributed in nature, with functional activity occurring in unicellular organisms, plants, fungi and animals. In most vertebrates, including humans, melatonin is synthes-ized primarily in the pineal gland and is regulated by the environmental light⁄dark cycle via the suprachiasmatic nucleus.

26p inspiron33 25-03-2013 37 4   Download

Signal transduction mediated by heterotrimeric G proteins regulates a wide variety of physiological functions. We are interested in the manipulation of G-protein-mediating signal transduction using G-protein-coupled receptors, which are derived from evolutionarily distant organisms and recognize unique ligands.

9p inspiron33 23-03-2013 47 5   Download

Transmissible spongiform encephalopathies are fatal neurodegenerative dis-eases that are caused by unconventional pathogens and affect the central nervous system of animals and humans. Several different forms of these dis-eases result from natural infection (i.e. exposure to transmissible spongiform encephalopathy agents or prions, present in the natural environment of the respective host).

18p galaxyss3 21-03-2013 37 2   Download

The lugwormArenicola marinainhabits marine sediments in which sulfide concentrations can reach up to 2 mm. Although sulfide is a potent toxin for humans and most animals, because it inhibits mitochondrial cyto-chromec oxidase at micromolar concentrations,A. marinacan use elec-trons from sulfide for mitochondrial ATP production.

9p media19 06-03-2013 34 4   Download