![](images/graphics/blank.gif)
Anti-cancer potential
-
Cancer is among the leading cause of death worldwide. Chemotherapy is commonly used in cancer management and among the challenges in managing cancer patients is renal insufficiency (RI), which can be due to cancer or anticancer treatment and can be potentiated by different factors.
8p
vikoch
27-06-2024
1
1
Download
-
Recent advances in the management of pancreatic neuroendocrine tumors (pNETs) highlight the potential benefits of temozolomide, an alkylating agent, for these patients. In this meta-analysis, we aimed to assess the outcome of temozolomide, alone or in combination with other anticancer medications in patients with advanced pNET.
15p
vikoch
27-06-2024
1
1
Download
-
Currently, L-asparaginase isolated from terrestrial microorganisms has been employed for anticancer industrial production. This enzyme has the function of inhibiting the growth of acute lymphoblastic leukemia, Hodgkin's lymphomas and other cancers. In this study, for the first time, L-asparaginase (ASNase) productive capacity of forty marine bacteria originating from Khanh Hoa sea of Viet Nam was screened and reported.
13p
viamancio
04-06-2024
1
0
Download
-
The winged-helix domain within the N-terminus of human MUS81 has been considered as potential target for drug development since the inhibition of this protein might significantly enhance the sensitivity of various cancer cells towards anticancer drugs. Nine cytotoxic triterpenoids previously purified from Helicteres hirsuta and Pterospermum truncatolobatum were selected for the docking experiment.
6p
dianmotminh02
03-05-2024
1
1
Download
-
Ebook "Handbook of anticancer drugs from marine origin" also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.
801p
tudohanhtau1006
29-03-2024
3
1
Download
-
Ebook "Medicinal chemistry and pharmacological potential of fullerenes and carbon nanotubes" particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances.
411p
manmanthanhla0201
27-02-2024
3
1
Download
-
The failure of current chemotherapeutic agents for pancreatic cancer (PCa) makes it the most aggressive soft tissue tumor with a 5-year survival of slightly above 10% and is estimated to be the second leading cause of cancer death by 2030.
16p
vileonardodavinci
23-12-2023
4
2
Download
-
In the last few decades, pyrazoline-based substances have emerged as potential antimicrobial and anticancer candidates. In concern with antimicrobial activity, this study aims to build a docking model to predict the structure of potential 2-pyrazoline derivatives. The cytotoxicity of some compounds was also evaluated to get insight into the structure–anticancer activity relationship of the 2- pyrazoline derivatives.
8p
vikissinger
21-12-2023
2
1
Download
-
To increase the chances of finding efficacious anticancer drugs, improve development times and reduce costs, it is of interest to rank test compounds based on their potential for human use as early as possible in the drug development process. In this paper, we present a method for ranking radiosensitizers using preclinical data.
19p
visharma
20-10-2023
4
2
Download
-
Streptomyces are considered the most potential microbes with the ability to produce antimicrobial and anticancer agents. These bacteria are found mostly in soil across the globe and play a pivotal role in material recycling processes. Isolation of Streptomyces in Vietnam has been conducted for years.
8p
vimulcahy
18-09-2023
3
3
Download
-
Over the past decades, researchers and scientists have paid more and more attention to the discovery of novel antibiotics and anticancer agents in fighting infection and cancer diseases. It is believed that endophytic actinomycetes from medicinal plants provide abundant resources for new compounds with significant bioactive properties. In the present study, we assessed antibacterial and cytotoxic activities of endophytic actinomycetes associated with Litsea cubeba (Lour.) Pers.
11p
vidudley
20-02-2023
7
2
Download
-
In this investigation, a new nanocomposite as a nanocarrier based on functionalized graphene oxide was synthesized by reaction of tetraethylenepentamine and chlorosulfonic acid with functional groups on the surface of GO. The synthesized nanocomposite was characterized by FT-IR, XRD TGA, FE-SEM, EDAX, TEM, and AFM analysis. To explore the potential of nanocomposites in drug delivery, the loading and releases of quercetin as an anticancer drug were investigated.
12p
lyhuyenthu
31-01-2023
3
2
Download
-
Monoaldehydes, due to natural origin and therapeutic activity, have attracted great attention for their ability to crosslink chitosan hydrogels for biomedical applications. However, most studies have focused on singlecomponent hydrogels. In this work, chitosan-based hydrogels, crosslinked for the first time with 2,3,4-trihydroxybenzaldehyde (THBA), were modified with pectin (PC), bioactive glass (BG), and rosmarinic acid (RA).
12p
viginny
30-12-2022
4
2
Download
-
Nano-sized materials have shown to have very high potential in anticancer therapy by an adequate tuning of their functionalization and physico-chemical properties. This study is focused on the synthesis and characterization of mesoporous silica nanoparticles (MSN) functionalized with a titanium(IV) or an organotin(IV) compound (therapeutic agents), fluorescein isothiocyanate (image agent) and transferrin (targeting molecule).
15p
vironald
15-12-2022
8
2
Download
-
Marine fungi are evaluated as a potential source for new natural compounds with bioactivities of pharmaceutical values. In this study, 66 fungal strains, isolated from 37 sponge samples in Nha Trang bay, were determined for cytotoxic activity against two human cancer cell lines, including cervical cancer (Hela) and breast cancer (MCF-7) cells using MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay.
7p
vipagani
24-10-2022
4
2
Download
-
During the cancer treatment path, cancer patients use numerous drugs, including anticancer, supportive, and other prescribed medications, along with herbs and certain products. This puts them at risk of significant drug interactions (DIs). This study describes DIs in cancer patients and their prevalence and predictors.
11p
vikolindagrabar
27-07-2022
3
2
Download
-
This review paper covers recent advances in the synthetic strategies for novel TPase inhibitors and their potential medicinal applications over the last few decades. A brief introduction covering the structural aspects of TPase inhibitors is also included to facilitate understanding of diverse approaches to monitor the design of new inhibitors. TPase is an essential enzyme and its inhibition is a potential target in the development of anticancer drugs.
28p
langthannam
29-12-2021
9
0
Download
-
Photodynamic therapy (PDT) applications enable light-controlled activation of drug candidates instead of their constitutive activities to prevent undesired side effects associated with their constant activities. A specific wavelength of light is utilized to enable electron mobility in the chemical structure, which results in differential activities that may alter cell viability and cellular functions. Canonical photodynamic therapy applications mostly focus on cytotoxicity-based antimicrobial and anticancer properties of the PDT agents.
9p
langthannam
29-12-2021
10
1
Download
-
In the present study, we have follwed the hydrothermal path for the synthesis of gold nanoparticles (Au NPs) from the biomaterial Elaeocarpus ganitrus seeds extract, which is a rapid, eco-friendly, non-chemical way. The prepared NPs were thoroughly analysed by powder x-ray diffraction and high resolution transmission electron microscopy studies and were also tested for anticancer studies.
7p
meyerowitz
25-12-2021
21
0
Download
-
The mustard species [(Brassica juncea (brown mustard), B. nigra (black mustard), B. rapa syn. B. campestris (field mustard or turnip), and Sinapis alba (white mustard or yellow mustard)] constitute important genetic resources and sources of raw materials to large number of agrobased industries in Turkey and elsewhere. S. alba is usually used as a condiment in dry form. B. nigra is used as a condiment and as vegetable with dietary fibre, vitamin C, and other anticancer compounds. B. juncea is used for oil and as spice. B. rapa is popularly used for biofuel raw material.
27p
tudichquannguyet
29-11-2021
10
1
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)