Antibiotic resistance

Enterococcus faecalis and E. faecium are prevalent pathogens in community and healthcare settings, often resistant to multiple antibiotics. This study aimed to assess the prevalence of virulence factors, drug resistance, and genetic determinants in clinical isolates in central Vietnam.

8p vihatake 06-01-2025 1 0   Download

In this study, we assessed the status of antibiotic resistance of H. pylori isolates to antimicrobial agents at Hospital of Hue University of Medicine and Pharmacy in Central Vietnam and identified the underlying molecular mechanisms related to tetracycline and amoxicillin resistance.

8p viharuno 03-01-2025 1 1   Download

Group B streptococcus (GBS) infections are still the leading cause of invasive infections in neonates, specically they also seriously cause mortality and morbidity with underlying diseases in adults. Curently, there are ten GBS serotypes (Ia, Ib, and II-IX) and the resistance characteristic of GBS is important to clinical treatment.

5p viharuno 03-01-2025 1 1   Download

According to statistical data of many countries in the wold, the more proportion of patients in hip replacement have, the more prosthetic infection have been treated. In Vietnam, treatment of prosthetic infection is often difficult beacause of antibiotic resistance, high cost treatment and difficult rehabilitation in post-surgery.

14p viuchiha 03-01-2025 2 1   Download

In Vietnam, a number of recent epidemiological studies demonstrated that the prevalence of antibiotic-resistant bacteria has been rapidly increasing, especially in intensive care units (ICUs). Objectives: For patients in the ICU of Hue University of Medicine and Pharmacy Hospital: (1) To survey of usage of antibiotics, and (2) to find out patient-related factors for antibiotic use.

10p viuchiha 03-01-2025 1 1   Download

The objectives of the thesis: Identify Salmonella isolated from pork, beef, and chicken meat at the retail markets in Hanoi. Determining antibiotic resistance characteristics of isolated Salmonella.

26p extraenglish 24-05-2021 31 3   Download

The objectives of the thesis: Identify Salmonella isolated from pork, beef, and chicken meat at the retail markets in Hanoi; determining antibiotic resistance characteristics of isolated Salmonella; analysis of related gene categories in multi-antibiotic resistant Salmonella.

26p larachdumlanat129 20-01-2021 17 5   Download

Describe the current situation and some related factors causing Hospital acquired pneumonia at the Department of Intensive care and Poison control in Thai Binh Provincial General Hospital in the years 2016-2017. Determine the infection rate and antibiotic resistance characteristics of some bacteria causing Hospital-acquired pneumonia in the Department of Intensive care and Poison control in Thai Binh Provincial General Hospital in the years 2016-2017.

27p angicungduoc6 21-07-2020 19 2   Download

India accounts for 30% of neonatal deaths globally. Bacterial sepsis is a significant cause of morbidity and mortality in newborns. The study helps to make antibiotic policy in neonatal sepsis. The main objective is to study the incidence of multidrug resistant gram negative and gram positive organisms causing neonatal septicemia and their antibiotic sensitivity pattern. The study was conducted in the Department of Microbiology over a period of one year. Sample of blood was collected under aseptic precautions and processed by standard techniques.

5p gaocaolon5 14-06-2020 26 3   Download

Insect pests and pathogens (fungi, bacteria and viruses) are responsible for severe crop losses. Insects feed directly on the plant tissues, while the pathogens lead to damage or death of the plant. Plants have evolved a certain degree of resistance through the production of defence compounds, which may be aproteic, e.g. antibiotics, alkaloids, terpenes, cyanogenic glucosides or proteic, e.g. chitinases,b-1,3-glu-canases, lectins, arcelins, vicilins, systemins and enzyme inhibitors.

16p research12 23-04-2013 44 3   Download

A novel cosmid (pABC6.5) whose DNA insert fromStrep-tomyces capreolus, the A201A antibiotic producer, overlaps the inserts of the previously reportedpCAR11 andpCAR13 cosmids, has been isolated. These two latter cosmids were known to contain the aminonucleoside antibiotic A201A resistance determinants ard2 and ard1, respectively. Together, these three cosmids have permitted the identifi-cation of a DNA stretch of 19 kbbetweenard1andard2, which should comprise a large region of a putative A201A biosynthetic (ata) gene cluster....

9p tumor12 22-04-2013 27 2   Download

Tetracycline repressor (TetR), which constitutes the most commonmechanismof bacterial resistance to an antibiotic, is a homodimeric protein composed of two identical sub-units, each of which contains a domain possessing a helix– turn–helix motif and a domain responsible for binding tetra-cycline. Binding of tetracycline in the protein pocket is accompanied by conformational changes in TetR, which abolish the specific interaction between the protein and DNA.

10p fptmusic 12-04-2013 41 1   Download

Horizontal gene transfer has been a major force for genome plasticity over evolutionary history, and is largely responsible for fitness-enhancing traits, including antibiotic resistance and virulence factors. In particular, for adap-tation of prokaryotes to extreme environments, lateral gene transfer seems to have played a crucial role.

9p inspiron33 25-03-2013 42 3   Download

Streptococcus pneumoniaeis one of the major pathogens worldwide. The use of currently available antibiotics to treat pneumococcal diseases is ham-pered by increasing resistance levels; also, capsular polysaccharide-based vaccination is of limited efficacy. Therefore, it is desirable to find targets for the development of new antimicrobial drugs specifically designed to fight pneumococcal infections.

13p inspiron33 23-03-2013 45 3   Download

Directed evolution is a useful tool in the study of enzymes. It is used in this study to investigate the means by which resistance to the antibiotic trimeth-oprim develops in dihyrofolate reductase fromEscherichia coli. Mutants with clinical levels of resistance were obtained after only three generations.

11p galaxyss3 21-03-2013 39 5   Download

The incidence of mixed viral⁄bacterial infections has increased recently because of the dramatic increase in antibiotic-resistant strains, the emer-gence of new pathogens, and the resurgence of old ones. Despite the relat-ively well-known role of viruses in enhancing bacterial infections, the impact of bacterial infections on viral infections remains unknown.

14p galaxyss3 19-03-2013 38 3   Download

ThewhiB-like genes (1-7) of Mycobacterium tuberculosisare involved in cell division, nutrient starvation, pathogenesis, antibiotic resistance and stress sensing. Although the biochemical properties of WhiB1, WhiB3 and WhiB4 are known, there is no information about the other proteins.

18p vinaphone15 27-02-2013 30 3   Download

The ever-increasing number of drug-resistant bacteria is a major challenge in healthcare and creates an urgent need for novel compounds for treat-ment. Host defense antimicrobial peptides have high potential to become the new generation of antibiotic compounds. Antimicrobial peptides consti-tute a major part of the innate defense system in all life forms.

9p viettel02 20-02-2013 44 3   Download

Antimicrobial peptides constitute one of the main classes of molecular weapons deployed by the innate immune system of all multicellular organisms to resist microbial invasion. A good proportion of all antimi-crobial peptides currently known, numbering hundreds of molecules, have been isolated from frog skin.

18p viettel02 20-02-2013 32 3   Download

The metallo-b-lactamase (MBL) GOB-1 was expressed via a T7 expression system in Escherichia coliBL21(DE3). The MBL was purified to homoge-neity and shown to exhibit a broad substrate profile, hydrolyzing all the tested b-lactam compounds efficiently.

12p cosis54 05-01-2013 45 4   Download