Antioxidant activity

Astaxanthin (AST) and pycnogenol (PYC) are natural bioactive compounds commonly used in pharmaceuticals and functional foods due to their highly antioxidant activity and potential health benefits. However, the widespread application of astaxanthin is hindered by its poor water solubility and highly unsaturated structure. In this study, nanoparticles co-delivering astaxanthin and pycnogenol (NAP) were fabricated to enhance the dispersibility, stability, and bioavailability of astaxanthin.

9p vifilm 11-10-2024 1 0   Download

Flavonoids, a diverse group of secondary metabolites, are known for their health-promoting properties, including antioxidant, anti-inflammatory, and anticancer activities. Phyllanthus amarus is a medicinal plant with extensive traditional use and it is a rich source of flavonoids. This study aimed to elucidate the gene expression in flavonoid biosynthesis in P. amarus.

7p vifilm 11-10-2024 5 1   Download

This study investigated the influence of culture media and culture time on the antioxidant and α-glucosidase inhibitory activities of the methanol extract obtained from the mycobiont of Graphis handelii. Different culture media, including MIX, PDA, and SAB4%, were employed to culture the mycobiont, and the biomass was harvested during different culture periods (4, 8, and 12 weeks).

9p viaburame 14-03-2025 0 0   Download

This study aimed to quantify the phenolic contents and the antioxidant capacities of leaf extract powders from three Myrtaceae plants, namely Cleistocalyx operculatus (Vietnamese name: Vối), Psidium guajava (Ổi), and Rhodomyrtus tomentosa (Sim), investigate their inhibitive activities on the growth of bacteria isolated from spoiled shrimps, and evaluate their values as preservative agents in the cold storage of Pacific whiteleg shrimps (Penaeus vannamei).

15p vibecca 01-10-2024 4 2   Download

Black mulberry is widely used in Vietnam because of its flavor and high nutritional value. This study aimed to examine the impact of pectinase enzyme concentration on the extraction recovery efficiency, total polyphenol content (TPC), anthocyanin content (ACN), antioxidant activity (DPPH), and turbidity of black mulberry juice.

9p viinuzuka 28-02-2025 2 1   Download

Zingiber Mill. is one of the most diverse genera in Vietnam with 36 recorded species, many of which have been used as traditional medicine to treat several ailments. Reports of studies on Z. nudicarpum D. Fang are relatively scarce. This study aimed to determine the microscopic characteristics, total phenolic content and antioxidant activity of Z. nudicarpum.

7p vihatake 06-01-2025 9 2   Download

Uvaria, a genus within the Annonaceae family, encompasses around 150 species of flowering plants. Uvaria boniana is extensively found throughout Vietnam and is utilized in traditional medicine practices. The aim of this study was to determine the microscopic characteristics and evaluate the antioxidant activity of Uvaria boniana.

6p viharuno 03-01-2025 2 2   Download

The present study was aimed at the determination of microscopic characteristics and chemical compositions as well as evaluating the antioxidant and acetylcholinesterase inhibitory activities of A. vietnamica.

8p viharuno 03-01-2025 4 2   Download

Avocado peel has been considered as a potential source of natural antioxidants in which phenolics are among the most important compounds. Therefore, this study aims to optimize the extraction process of phenolics using response surface methodology and evaluate the corresponding antioxidant activity.

11p viuchiha 03-01-2025 6 2   Download

Keeping in view the potential of probiotics and antioxidative properties of herbs, the present study was endeavoured to develop antioxidant-rich herbal lassi using carrot, ginger, and turmeric extract and assess the antioxidant activity of the developed lassi.

10p chauchaungayxua11 23-03-2021 15 3   Download

Obtaining of secondary metabolites from marine fungi isolated in the Central Vietnam and identifying some biological activities (antibiotimicrobial, cytotoxic, antioxidant, neuroprotective activities) of obtained individual compounds.

27p trinhthamhodang7 31-08-2020 44 2   Download

A series of semicarbazones, thiosemicarbazones, 1,3,4-oxadiazoles/thiadiazoles bearing pyrazole scaffold were designed and synthesized. All the synthesized new compounds were characterized by 1H NMR, 13C NMR, MS and elemental analysis.

14p tocectocec 26-05-2020 31 2   Download

New ruthenium(III) complexes with 3-(Benzothiazol-2-yliminomethyl)-phenol (HL) ligand have been synthesized and characterized with the aid of elemental analysis, IR, electronic, and electron paramagnetic resonance spectroscopic techniques.

12p tocectocec 25-05-2020 12 3   Download

A series of novel 5-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine linked various sulfonamide derivatives 8a-8j poly functionalized were designed and synthesized in moderate to good yield.

10p tocectocec 25-05-2020 16 1   Download

Nuclear factor erythroid-2 related factor 2 (Nrf2) is a crucial transcription factor that regulates the expression of defensive antioxidants and detoxification enzymes in cells. In a previous study, we showed that expression of the Nrf2 gene is regulated by an epigenetic modification. Rauvolfia verticillata, a traditional Chinese herbal medicine widely used in China, possesses anticancer and antioxidant effects. In this study, we investigated how Nrf2 is epigenetically regulated by reserpine, the main active component in R. verticillata, in mouse skin epidermal JB6 P+ cells.

11p caothientrangnguyen 09-05-2020 19 2   Download

This study investigated the enzymatic function of two putative plant GPXs, GPXle1 from Lycopersicon esculentum and GPXha2 from Helianthus annuus, which show sequence identities with the mammalian phospholipid hydroperoxide glutathione peroxidase (PHGPX). Both purified recombinant proteins expressed in Escherichia coli show PHGPX activity by reducing alkyl, fatty acid and phospholipid hydroperoxides but not hydrogen peroxide in the presence of glutathione.

7p research12 01-06-2013 39 4   Download

Reactive oxygen species (ROS) are products of normal metabolic activities and are thought to be the cause of many diseases. A selenium-containing single-chain abzyme 2F3 (Se-2F3-scFv) that imitates glutathione peroxidase has been produced which has the capacity to remove ROS. To evaluate the antioxidant ability of Se-2F3-scFv, we con-structeda ferrous sulfate/ascorbate (Vc/Fe 2+ )-inducedmito-chondrial damage model system and investigated the capacity of Se-2F3-scFv to protect mitochondria from oxi-dative damage.

6p tumor12 20-04-2013 35 4   Download

Thioredoxins are a group of small redox-active proteins involved in cellular redox regulatory processes as well as antioxidant defense. Thioredoxin, glutaredoxin, and try-paredoxin are members of the thioredoxin superfamily and share structural and functional characteristics. In the mal-arial parasite, Plasmodium falciparum, a functional thio-redoxin and glutathione system have been demonstrated and are considered to be attractive targets for antimalarial drug development.

8p tumor12 20-04-2013 44 3   Download

Leucine zipper-bearing kinase (LZK) is a novel member of themixed lineage kinase (MLK) family [Sakuma, H., Ikeda, A.,Oka,S.,Kozutsumi,Y.,Zanetta,J.P., andKawasaki, T. (1997)J. Biol.Chem.272, 28622–28629].Wehavepreviously shown that LZK activates the c-Jun-NH2terminal kinase (JNK) pathway, but not the extracellular signal-related kinase (ERK) pathway, by acting as a mitogen-activated protein kinase kinase kinase (MAPKKK) [Ikeda, A., Hasegawa, K., Masaki, M., Moriguchi, T., Nishida, E., Kozutsumi, Y., Oka, S., and Kawasaki, T. (2001)J. Bio-chem.130, 773–781]....

8p tumor12 20-04-2013 26 3   Download

H2O2 generation is a limiting step in thyroid hormone bio-synthesis. Biochemical studies have confirmed that H2O2is generated by a thyroid Ca 2+ /NADPH-dependent oxidase. Decreased H2O2 availability may be another mechanism of inhibition of thyroperoxidase activity produced by thio-ureylene compounds, as propylthiouracil (PTU) and methimazole (MMI) are antioxidant agents. Therefore, we analyzed whether PTU or MMI could scavenge H2O2or inhibit thyroidNADPHoxidase activityin vitro.

6p fptmusic 16-04-2013 48 3   Download