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Atypical protein kinase C
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Protein kinase C iota (PKCι) and protein kinase C zeta (PKCζ) are two atypical protein kinase (aPKC) enzymes that contribute to cell proliferation and cancer development. The Hippo/YAP pathway is commonly disrupted and upregulated in cancers.
12p
vikuala271
13-06-2020
10
0
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When nucleotide hydrolysis is prevented, agonists of the P2Y12 receptor enhance the proliferation of C6 glioma cells by RhoA-dependent, protein kinase C (PKC)-dependent activation of the extracellular signal-regulated kinase (ERK) pathway [Claes P, Grobben B, Van Kolen K, Roymans D & Slegers H (2001)Br J Pharmacol134, 402–408; Grobben B, Claes P, Van Kolen K, Roymans D, Fransen P, Sys SU & Slegers H (2001)J Neurochem 78, 1325–1338].
12p
inspiron33
26-03-2013
35
4
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