Becoming a Translator

Xem 1-5 trên 5 kết quả Becoming a Translator

Báo cáo khoa học: Differential post-translational modiﬁcation of CD63 molecules during maturation of human dendritic cells

The capacity of dendritic cells to initiate T cell responses is related to their ability to redistribute MHC class II mole-cules from the intracellular MHC class II compartments to the cell surface. This redistribution occurs during dendritic cell development as they are converted from an antigen capturing, immature dendritic cell into an MHC class II-peptide presenting mature dendritic cell. During this matu-ration, antigen uptake and processing are down-regulated and peptide-loaded class II complexes become expressed in a stable manner on the cell surface. ...

9p fptmusic 16-04-2013 45 3 Download

Báo cáo khoa học: Efﬁcient synthesis of a disulﬁde-containing protein through a batch cell-free system from wheat germ

We have developed a highly productive cell-free protein synthesis system from wheat germ, which is expected to become an important tool for postgenomic research. However, this system has not been optimized for the synthesis of disulfide-containing proteins. Thus, we sear-ched here for translation conditions under which a model protein, a single-chain antibody variable fragment (scFv), could be synthesized into its active form.

7p fptmusic 12-04-2013 29 3 Download

Báo cáo khoa học: Mammalian transglutaminases Identification of substrates as a key to physiological function and physiopathological relevance

Transglutaminases form a large family of intracellular and extracellular enzymes that catalyse the Ca 2+ -dependent post-translational modification of proteins. Despite significant advances in our understanding of the biolo-gical role of most mammalian transglutaminase isoforms, recent findings suggest new scenarios, most notably for the ubiquitous tissue transglutami-nase.

17p awards 05-04-2013 43 3 Download
Báo cáo khoa học: Post-translational cleavage of recombinantly expressed nitrilase from Rhodococcus rhodochrous J1 yields a stable, active helical form

Nitrilases convert nitriles to the corresponding carboxylic acids and ammo-nia. The nitrilase fromRhodococcus rhodochrousJ1 is known to be inactive as a dimer but to become active on oligomerization. The recombinant enzyme undergoes post-translational cleavage at approximately residue 327, resulting in the formation of active, helical homo-oligomers.

10p galaxyss3 19-03-2013 35 6 Download
Network Address Translation (NAT)

NAT was developed to address a couple of concerns. First, the number of public IP addresses available on the Internet was becoming depleted

4p chutieuchuathieulam 23-07-2010 125 31 Download