Biological sequence analysis

Ebook "Discovering biomolecular mechanisms with computational biology" present critical reviews of methods and high-impact applications in computational biology that lead to results that also non-bioinformaticians must know to design efficient experimental research plans. Discovering Biomolecular Mechanisms with Computational Biology also summarizes non-trivial theoretical predictions for regulatory and metabolic networks that have received experimental confirmation.

152p ladongphongthanh1008 22-04-2024 8 2   Download

Ebook "Introduction to computational biology: An evolutionary approach" Analysis of molecular sequence data is the main subject of this introduction to computational biology. There are two closely connected aspects to biological sequences: (i) their relative position in the space of all other sequences, and (ii) their movement through this sequence space in evolutionary time. Accordingly, the first part of the book deals with classical methods of sequence analysis: pairwise alignment, exact string matching, multiple alignment, and hidden Markov models.

329p tracanhphuonghoa1007 22-04-2024 10 2   Download

The human plasma proteome is important for many biological processes and targets for diagnostics and therapy. It is therefore of great interest to understand the interplay of genetic and environmental factors to determine the specific protein levels in individuals and to gain a deeper insight of the importance of genetic architecture related to the individual variability of plasma levels of proteins during adult life.

16p vibransone 28-03-2024 5 2   Download

Congenital heart disease (CHD) occurs in almost 1% of newborn children and is considered a multifactorial disorder. CHD may segregate in families due to significant contribution of genetic factors in the disease etiology. The aim of the study was to identify pathophysiological mechanisms in families segregating CHD.

13p vibransone 28-03-2024 4 2   Download

Expression quantitative trait loci (eQTL) analysis is a powerful method to detect correlations between gene expression and genomic variants and is widely used to interpret the biological mechanism underlying identified genome wide association studies (GWAS) risk loci.

15p vioraclene 31-03-2024 4 2   Download

Ebook "Biogas science and technology (Advances in Biochemical engineering/biotechnology, Volume 151)" provides readers with contents including: microbiology and molecular biology tools for biogas process analysis, diagnosis and control; anaerobic fungi and their potential for biogas production; hygiene and sanitation in biogas plants;...

200p tudohanhtau1006 29-03-2024 2 1   Download

Ebook "Systems analysis of human multigene disorders" Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors.

134p duongthandue0501 28-02-2024 1 1   Download

The advancement of single-cell sequencing has progressed our ability to solve biological questions. Cell type annotation is of vital importance to this process, allowing for the analysis and interpretation of enormous single-cell datasets. At present, however, manual cell annotation which is the predominant approach remains limited by both speed and the requirement of expert knowledge.

18p vicwell 29-02-2024 5 2   Download

Ebook "High-performance in-memory genome data analysis: How in-memory database technology accelerates personalized medicine" provide details on innovative approaches to enabling the processing, combination, and analysis of relevant data in real-time. The book bridges the gap between medical experts, such as physicians, clinicians, and biological researchers, and technology experts, such as software developers, database specialists, and statisticians.

239p manmanthanhla0201 26-02-2024 7 1   Download

Ebook "Advances in wheat genetics: From genome to field (Proceedings of the 12th International wheat genetics symposium)" provides a comprehensive review of the forefront of wheat research, across various important topics such as germplasm and genetic diversity, cytogenetics and allopolyploid evolution, genome sequencing, structural and functional genomics, gene function and molecular biology, biotic stress, abiotic stress, grain quality, and classical and molecular breeding.

421p manmanthanhla0201 26-02-2024 3 1   Download

Ebook "Pattern recognition in bioinformatics: 5th IAPR international conference, PRIB 2010 Nijmegen, The Netherlands, September 22-24, 2010 proceedings" has two main objectives: the creation and maintenance of biological databases and the analysis of life sciences data in order to unravel the mysteries of biological function. Computer science methods such as pattern recognition, machine learning, and data mining have a great deal to offer the field of bioinformatics.

458p tachieuhoa 28-01-2024 4 2   Download

Ebook "RNA detection: Methods and protocols" introduces different concepts and methods of detecting RNA in biological material in a variety of model systems. The chapters in this book discuss methods that will answer numerous biological questions that arise in the study of RNAs. Some of the topics covered in this book are single mRNA molecule detection in embryos and neurons; detection of mRNA and associated molecules by ISH-IEM on frozen sections; optimizing molecular beacons for intracellular analysis of RNA;...

492p lucchinguyen 28-12-2023 6 2   Download

Ebook Bioinformatics for geneticists includes contents: Section I: An introduction to bioinformatics for the geneticist; Section II: The impact of complete genome sequences on genetics; Section III: Bioinformatics for genetic study design; Section IV: Biological sequence analysis and characterization; Section V: Genetics/genomics interfaces.

423p haojiubujain08 01-11-2023 10 2   Download

Ebook "Developing bioinformatics computer skills" includes content: Audience for this book, biology in the computer age, computational approaches to biological questions, setting up your workstation, files and directories in unix, working on a unix system, biological research on the web, sequence analysis, pairwise alignment, and database searching,...and other contents.

344p haojiubujain07 20-09-2023 4 2   Download

Whole-genome doubling (WGD) is a common mutation in cancer. Various studies have suggested that WGD is associated with a poor prognosis in cancer. However, the detailed association between WGD occurrence and prognosis remains unclear. In this study, we aimed to elucidate the mechanism by which WGD affects prognosis using sequencing data from the Pan-Cancer Analysis of Whole Genomes (PCAWG) and The Cancer Genome Atlas.

15p vioracle 29-09-2023 4 3   Download

MicroRNAs (miRNAs) regulate many biological processes by post-translational gene silencing. Analysis of miRNA expression profiles is a reliable method for investigating particular biological processes due to the stability of miRNA and the development of advanced sequencing methods.

9p vinarcissa 21-03-2023 7 2   Download

Cyclic nucleotide-gated channels (CNGCs) are ligand-gated calcium signaling channels, play vital biological functions. Nonetheless, the CNGC gene families have not been well studied in Brassicaceae which includes commercially important and evolutionary model crops. Here, using in silico approaches, we recognized 414 CNGC genes in sixteen sequenced genomes of Brassicaceae species, which represent 10 genera of 8 tribes, ranging between 10‒51 genes.

53p lyhuyenthu 31-01-2023 8 2   Download

This study aims to compare microRNA expression levels in wt and Bag-1 knockout (KO) MCF-7 breast cancer cells. hsa-miR-429 was selected as a potential miRNA in BAG-1KO MCF-7 cells because of the downregulation both in bioinformatics and validation qRT-PCR assay. According to predicted mRNA targets and functional enrichment analysis the ten hub proteins that are phosphatidylinositol4,5-biphosphate 3-kinase catalytic subunit alpha (PIK3CA), kinase insert domain receptor (KDR), GRB2 associated binding protein 1 (GAB1).

30p lyhuyenthu 31-01-2023 2 2   Download

Long non-coding RNAs (lncRNAs) have crucial roles in various biological regulatory processes. However, the study of lncRNAs is limited in woody plants. Catalpa bungei is a valuable ornamental tree with a long cultivation history in China, and a deeper understanding of the floral transition mechanism in C. bungei would be interesting from both economic and scientific perspectives.

16p vihagrid 30-01-2023 8 3   Download

Long non-coding RNAs (lncRNAs) are widely involved in the pathogenesis of cancers. However, biological roles of lncRNAs in occurrence and progression of colorectal cancer (CRC) remain unclear. The current study aimed to evaluate the expression pattern of lncRNAs and messenger RNAs (mRNAs).

11p vikolindagrabar 27-07-2022 4 1   Download