bridge’s structure

The Performance-Based Seismic Design (PBSD) is an advanced approach to designing earthquake-resistant structures, ensuring that a building meets specific performance objectives under seismic impacts. Unlike traditional design codes, PBSD aims to predict and control the damage to structures based on defined earthquake levels, minimizing damage and repair costs after an earthquake.

7p vibenya 31-12-2024 3 2   Download

Tensegrity is a structural system constructed of tensile cables and compressive bars. This thesis proposes several general methods for creating tensegrity structures. The author has developed new methods for creating specific tensegrity cells and the corresponding computer code. Furthermore, the author has constructed various physical models to validate the methods. A proposal for an observation tower on top of the Eureka building in Melbourne has also been devised by the author.

88p runthenight07 01-03-2023 7 3   Download

Determine the coefficient of water permeability, waterproofing marks, chloride ion diffusion coefficients of some types of concrete commonly used in bridge construction subjected to pre-compressive and direct-compression loads. Develop a predictive model for life expectancy using reinforced concrete bridges taking into consideration the effect of the load according to the criteria of initial corrosion of reinforcement in concrete. Application of life expectancy for the structure of reinforced concrete bridges.

27p kequaidan7 01-09-2020 30 2   Download

The purpose of this paper is to explore the effect of tripartite social capital (bonding, bridging and linking) on managers’ resilience building and to examine the underlying mechanism through which these relationships exist.

18p tocectocec 24-05-2020 19 2   Download

Objectives of the dissertation: Research to improve the synthesis process of erlotinib hydrochloride drugs. Research on the synthesis and determination of quinazoline derivative structure. Research on the synthesis and determination of the structure of hybrid compounds of quinazoline derivatives and azides via triazole bridges.

26p xacxuoc4321 08-07-2019 33 5   Download

Đề tài nghiên cứu nguyên lý vận hành của hệ thống không dây Wireless Structural Bridges Testing System; ứng dụng công nghệ Wireless Structural Bridges Testing System trong công tác quan trắc và phân tích dao động các công trình cầu. Mời các bạn cùng tham khảo.

33p bautroibinhyen26 03-05-2017 81 5   Download

Research objectives: To form a direct, simple and easy-to-use methodology to determine the redundancy of bridge’s structure. Form a finite element method in order to take into account the nonlinear behavior of the structure, when one or some of the main structure part is failure.

19p change03 06-05-2016 53 1   Download

FTIR spectroscopy has been applied to study the coordination structures of Mg2þ and Ca2þ ions bound in Akazara scallop troponin C (TnC), which contains only a single Ca2þ binding site. The region of the COO – antisymmetric stretch provides information about the coordination modes of COO – groups to the metal ions: bidentate, unidentate, or pseudo-bridging. Two bands were observed at 1584 and 1567 cm21 in the apo state, whereas additional bands were observed at 1543 and 1601 cm21 in the Ca2þ-bound and Mg2þ-bound states, respectively.

7p system191 01-06-2013 43 2   Download

Laboratory for Phytopathology and Plant Protection, Katholieke Universiteit Leuven, Belgium; 2Institut de Pharmacologie et Biologie Structurale, UMR-CNRS 5089, Toulouse Cedex, France; 3Rega Institute, Laboratory of Molecular Immunology, Katholieke Universiteit Leuven, Belgium Fruits of elderberry (Sambucus nigra) express small quantities of a type-2 ribosome-inactivating protein with an exclusive specificity towards the NeuAc(a2,6)Gal/GalNAc disaccharide and a unique molecular structure typified by the occurrence of a disulfide bridge between the B-chains of two adjacent protomers....

10p system191 01-06-2013 43 3   Download

The cloned guinea-pig Y2 neuropeptide Y (NPY) receptors expressed in Chinese hamster ovary (CHO) cells, as well as the Y2 receptors natively expressed in rat forebrain, are distributed in two populations. A smaller population that is readily accessed by agonist peptides on the surface of intact cells constitutes less than 30% of Y2 receptors detected in particulates after cell homogenization. A much larger fraction of cell surface Y2 sites can be activated by sulfhydryl modifiers.

8p research12 01-06-2013 42 4   Download

We report the isolation of a novel antimicrobial peptide, bass hepcidin, from the gill of hybrid striped bass, white bass (Morone chrysops) · striped bass (M. saxatilis). After the intraperitoneal injection of Micrococcus luteus and Escherichia coli, the peptide was purified from HPLC fractions with antimicrobial activity against Escherichia coli. Sequencing by Edman degradation revealed a 21-residue peptide (GCRFCCNCCPNMSGCGVCCRF) with eight putative cysteines.

6p research12 01-06-2013 30 5   Download

The solution structure of a synthetic mutant type I antifreeze protein (AFP I) was determined in aqueous solution at pH 7.0 using nuclear magnetic resonance (NMR) spectroscopy. The mutations comprised the replacement of the four Thr residues by Val and the introduction of two additional Lys-Glu salt bridges. The antifreeze activity of this mutant peptide, VVVV2KE, has been previously shown to be similar to that of the wild type protein, HPLC6 (defined here as TTTT).

8p research12 01-06-2013 36 4   Download

2S albumin storage proteins fromrapeseed (Brassica napus), called napins, consist of two different polypeptide chains linked by disulphide bridges, which are derived by proteo-lytic cleavage froma single precursor. The precursor formof the napin BnIb (proBnIb) has been cloned using a PCR strategy and sequenced.

8p research12 29-04-2013 40 2   Download

All living organisms contain redox systems involving thior-edoxins (Trx), proteins featuringanextremelyconservedand reactive active site that perform thiol-disul®de interchanges with disul®de bridges of target proteins. In photosynthetic organisms, numerous isoforms of Trx coexist, as revealedby sequencing ofArabidopsisgenome. The speci®c functions of many of them are still unknown.

11p research12 29-04-2013 34 2   Download

We previously purified and characterized a peptide toxin, birtoxin, from the South African scorpion Parabuthus transvaalicus. Birtoxin is a 58-residue, long chain neurotoxin that has a unique three disulfide-bridged structure. Here we report the isolation and characterization of ikitoxin, a pep-tide toxin with a single residue difference, and a markedly reducedbiological activity, frombirtoxin. Bioassays onmice showed that high doses of ikitoxin induce unprovoked jumps, whereas birtoxin induces jumps at a 1000-fold lower concentration. ...

8p tumor12 22-04-2013 41 3   Download

The chaperone calreticulin is a highly conserved eukaryotic protein mainly located in the endoplasmic reticulum. It contains a free cysteine SH group but does not form disul-fide-bridged dimers under physiological conditions,indica-ting that the SH group may not be fully accessible in the native protein. Using PAGE,urea gradient gel electro-phoresis,capillary electrophoresis and MS,we show that dimerization through the SH group can be induced by lowering the pH to 5–6,heating,or under conditions that favour partial unfolding such as urea concentrations above 2.

9p tumor12 20-04-2013 41 4   Download

Pi4 is a38-residue toxincross-linkedby fourdisulfidebridges that has been isolated from the venom of the Chactidae scorpion Pandinus imperator. Together with maurotoxin, Pi1, Pi7 andHsTx1, Pi4belongs to theaKTX6 subfamilyof short four-disulfide-bridged scorpion toxins acting on K + channels. Due to its very low abundance in venom, Pi4 was chemically synthesized in order to better characterize its pharmacology and structural properties.

10p tumor12 20-04-2013 32 1   Download

Neutralizing and protective monoclonal antibodies (mAbs) were used to fine-map the highlyconserved hemagglutinin noose epitope (H379–410, HNE) of themeasles virus. Short peptides mimicking this epitope were previouslyshown to induce virus-neutralizing antibodies [El Kasmi et al. (2000) J. Gen. Virol.81, 729–735]. The epitope contains three cys-teine residues, two of which (Cys386 and Cys394) form a disulfide bridge critical for antibodybinding.

13p tumor12 20-04-2013 37 5   Download

X-ray crystallography of the nonheme manganese catalase fromLactobacillus plantarum(LPC) [Barynin, V.V., Whit-taker, M.M., Antonyuk, S.V., Lamzin, V.S., Harrison, P.M., Artymiuk, P.J. & Whittaker, J.W. (2001)Structure9, 725–738] has revealed the structure of the dimanganese redox cluster together with its protein environment. The oxidized [Mn(III)Mn(III)] cluster is bridged by two solvent molecules (oxo and hydroxo, respectively) together with a l1,3bridging glutamate carboxylate and is embedded in a web of hydrogen bonds involving an outer sphere tyrosine residue (Tyr42). ...

15p tumor12 20-04-2013 29 6   Download

To elucidate the structural features of the mussel defensin MGD1 required for antimicrobial activity, we synthesized a series of peptides corresponding to the main known secon-dary structures of the molecule and evaluated their activity towards Gram-positive and Gram-negative bacteria, and filamentous fungi. We found that the nonapeptide corres-ponding to residues 25–33 of MGD1 (CGGWHRLRC) exhibited bacteriostatic activity once it was cyclized by a non-naturally occurring disulfide bridge.

9p fptmusic 16-04-2013 49 2   Download