Cancer of the skin

To assess the clinical characteristics, subclinical and results of treatment of basal cell carcinoma. After 02 years of treating 48 cases of facial basal cell carcinoma, the authors make some conclusions on epidemiological, clinical issues related to skin cancer, suggesting suitable surgical approaches, and covering the defects of face after surgery.

4p vinatisu 29-08-2024 1 0   Download

The study aimed to determine the incidence and severity of postoperative complications in early breast cancer (BC) females undergoing immediate breast reconstruction (IBR) with implant and polypropylene mesh (PPM) after nipple-sparing mastectomy (NSM).

8p vinatisu 23-08-2024 1 1   Download

Malignant melanoma is an aggressive skin cancer and a tumor of melanocytic origin. Recent studies have suggested that long non-coding RNAs (lncRNAs) play crucial regulatory roles in multiple malignancies, including melanoma. Testis expressed 41 (TEX41) is a relatively new lncRNA whose mechanism in melanoma remains vague.

14p vielonmusk 21-01-2022 13 0   Download

Considering that exposure to sunlight in childhood and adolescence has an important role in skin cancer, so it seems that training protective behaviors in this period is more effective. Objectives: To survey the application of protection motivation theory (PMT) on skin cancer preventive behaviors among students in rural areas of Fasa city, Iran.

10p vielonmusk 21-01-2022 14 1   Download

The importance of assessing and monitoring the health status of a population has grown in the last decades. Consistent and high quality data on the morbidity and mortality impact of a disease represent the key element for this assessment.

10p vielonmusk 21-01-2022 15 1   Download

Nuclear factor erythroid-2 related factor 2 (Nrf2) is a crucial transcription factor that regulates the expression of defensive antioxidants and detoxification enzymes in cells. In a previous study, we showed that expression of the Nrf2 gene is regulated by an epigenetic modification. Rauvolfia verticillata, a traditional Chinese herbal medicine widely used in China, possesses anticancer and antioxidant effects. In this study, we investigated how Nrf2 is epigenetically regulated by reserpine, the main active component in R. verticillata, in mouse skin epidermal JB6 P+ cells.

11p caothientrangnguyen 09-05-2020 16 2   Download

Two novel bradykinin-related peptides (Ala3,Thr6)-bra-dykinin and (Val1,Thr3,Thr6)-bradykinin, were identified by a systematic sequencing study of peptides in the defensive skin secretion of the yellow-bellied toad,Bombina variegata. These peptides are the first amphibian skin bradykinins to exhibit amino acid substitutions at the Pro3 position of the bradykinin nonapeptide.

8p research12 29-04-2013 36 4   Download

A large number of bioactive peptides have been isolated from amphibian skin secretions. These peptides have a variety of actions including antibiotic and anticancer acti-vities and the inhibition of neuronal nitric oxide synthase. We have investigated the structure–activity relationship of citropin 1.1, a broad-spectrum antibiotic and anticancer agent that also causes inhibition of neuronal nitric oxide synthase, by making a number of synthetically modified analogues.

13p tumor12 20-04-2013 37 3   Download

In our continued studies on corticotropin releasing factor receptor (CRFR1) signaling in the skin, we tested functional activity of CRFR1a, e, f, g and h isoforms after transfection to COS cells.Both membrane-bound and soluble variants are translatedin vivointofinal proteinproducts that undergo further post-translational modifications.

10p dell39 03-04-2013 40 3   Download

Anovel photoprotectivemycosporinewas isolated fromthe lichenized ascomyceteCollema cristatum. Biological activity was measured in terms of protection against UV-B induced membrane destruction and pyrimidine dimer formation in cultured human keratinocytes, and prevention of UV-B induced erythema. It was found that the pure isolated compound prevented UV-B induced cell destruction in a dose-dependent manner, that the compound partially pre-vented pyrimidine dimer formation and completely preven-ted UV-B induced erythema when applied to the skin prior to irradiation....

5p dell39 03-04-2013 42 4   Download

Transglutaminase 1 (TGase 1) is an essential enzyme for cornified enve-lope formation in stratified squamous epithelia. This enzyme catalyzes the cross-linking of glutamine and lysine residues in structural proteins in differentiating keratinocytes. To gain insight into the preferred substrate structure of TGase 1, we used a phage-displayed random peptide library to screen primary amino acid sequences that are preferentially selected by human TGase 1.

11p vinaphone15 28-02-2013 32 2   Download

Antimicrobial peptides constitute one of the main classes of molecular weapons deployed by the innate immune system of all multicellular organisms to resist microbial invasion. A good proportion of all antimi-crobial peptides currently known, numbering hundreds of molecules, have been isolated from frog skin.

18p viettel02 20-02-2013 31 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Individual and setting level predictors of the implementation of a skin cancer prevention program: a multilevel analysis

13p toshiba22 22-11-2011 60 4   Download

1 March 2004 Genome Biology 2004, 5:R16 The electronic version of this article is the complete one and can be found online at http://genomebiology.com/2004/5/3/R16 Received: 27 October 2003 Revised: 15 December 2003 Accepted: 22 January 2004 © 2004 Casati and Walbot; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. B fluence ratesof skin cancer and has raised terrestrial levels of ultraviolet-Bfor plants....

0p thulanh21 15-11-2011 60 1   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: The initial experience of electronic brachytherapy for the treatment of non-melanoma skin cancer...

8p toshiba9 14-10-2011 40 3   Download

Other Gram-Negative Bacteria Achromobacter xylosoxidans A. xylosoxidans (previously Alcaligenes xylosoxidans) is probably part of the endogenous intestinal flora and has been isolated from water sources. Immunocompromised hosts, including patients with cancer and post- chemotherapy neutropenia, cirrhosis, and chronic renal failure, are at increased risk. Nosocomial outbreaks of A. xylosoxidans infection have been attributed to contaminated fluids, and clinical illness has been associated with isolates from many sites, including blood (often in the setting of intravascular devices).

5p colgate_colgate 21-12-2010 83 3   Download

Etiology Humoral hypercalcemia of malignancy (HHM) occurs in up to 20% of patients with cancer. HHM is most common in cancers of the lung, head and neck, skin, esophagus, breast, genitourinary tract, and in multiple myeloma and lymphomas. Several distinct humoral causes of HHM occur, most commonly overproduction of PTHrP. In addition to acting as a circulating humoral factor, bone metastases (e.g., breast, multiple myeloma) may produce PTHrP, leading to local osteolysis and hypercalcemia.

5p thanhongan 07-12-2010 79 3   Download

The Palpable Breast Mass Women should be strongly encouraged to examine their breasts monthly. A potentially flawed study from China has suggested that BSE does not alter survival, but given its safety, the procedure should still be encouraged. At worst, this practice increases the likelihood of detecting a mass at a smaller size when it can be treated with more limited surgery. Breast examination by the physician should be performed in good light so as to see retractions and other skin changes.

5p konheokonmummim 03-12-2010 63 2   Download

Harrison's Internal Medicine Chapter 86. Breast Cancer Breast Cancer: Introduction Breast cancer is a malignant proliferation of epithelial cells lining the ducts or lobules of the breast. In the year 2007, about 180,510 cases of invasive breast cancer and 40,910 deaths occurred in the United States. Epithelial malignancies of the breast are the most common cause of cancer in women (excluding skin cancer), accounting for about one-third of all cancer in women.

5p konheokonmummim 03-12-2010 85 5   Download

Other Nonmelanoma Cutaneous Malignancies Neoplasms of cutaneous adnexa and sarcomas of fibrous, mesenchymal, fatty, and vascular tissues make up 1–2% of NMSC (Table 83-6). Some can portend a poor prognosis such as Merkel cell carcinoma, which is a neural crestderived, highly aggressive malignancy that exhibits a metastatic rate of 75% and a 5-year survival rate of 30–40%. Others, such as the human herpes virus 8-induced, HIV-related Kaposi's sarcoma, exhibit a more indolent course.

8p konheokonmummim 03-12-2010 79 7   Download