Cannabinoids

Less than 20 years ago the field of cannabis and the cannabinoids was still considered a minor, somewhat quaint, area of research. A few groups were active in the field, but it was already being viewed as stagnating. The chemistry of cannabis was well known, Δ9-tetrahydrocannabinol (Δ9-THC), identified in 1964, being the only major psychoactive constituent and cannabidiol, which is not psychoactive, possibly contributing to some of the effects. These cannabinoids and several synthetic analogs had been thoroughly investigated for their pharmacological effects.

754p mnemosyne75 02-02-2013 22 4   Download

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Functional Role of Serine Residues of Transmembrane Dopamin VII in Signal Transduction of CB2 Cannabinoid Receptor

7p hoami_266 15-09-2011 32 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis...

14p thulanh14 15-10-2011 35 2   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation...

38p thulanh26 09-12-2011 32 2   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation

13p panasonic09 12-01-2012 27 2   Download

Public opinion on the medical value of marijuana has been sharply divided. Some dismiss medical marijuana as a hoax that exploits our natural compassion for the sick; others claim it is a uniquely soothing medicine that has been withheld from patients through regulations based on false claims. Proponents of both views cite “scientific evidence” to support their views and have expressed those views at the ballot box in recent state elections.

286p camchuong_1 10-12-2012 32 2   Download

The endocannabinoid system is a conserved system involved in the modula-tion of several physiologic processes, from the activity of the central ner-vous system to reproduction. Type 1 cannabinoid receptor (CNR1) cDNA was cloned from the brain and testis of the anuran amphibian, the frog Rana esculenta.

12p galaxyss3 19-03-2013 21 2   Download

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: SR144528 as Inverse Agonist of CB2 Cannabinoid Receptor

6p hoami_266 15-09-2011 27 1   Download

We have investigated the existence of a precoupled form of the distal C-ter-minal truncated cannabinoid receptor 1 (CB1-417) and heterotrimeric G proteins in a heterologous insect cell expression system. CB1-417 showed higher production levels than the full-length receptor. The production lev-els obtained in our expression system were double the values reported in the literature.

10p media19 05-03-2013 14 1   Download

Loss of cannabinoid receptors (CB1) occurs prior to neuro-degeneration in Huntington’s disease (HD). The levels and distribution of CB1 RNA were equivalent in 3-week-old mice regardless of genotype demonstrating that the specific factors and appropriate chromatin structure that lead to the transcription ofCB1were present in the striatum of young R6/2 and R6/1 transgenic HD mice.

12p awards 05-04-2013 26 1   Download

(bq) part 1 book “cannabis - a clinician’s guide” has contents: cannabinoids and the entourage effect, cannabis and addiction, what should we tell our patients about marijuana, cannabinoid medications for treatment of neurological disorders, terpenes,… and other contents.

173p tieu_vu15 07-09-2018 7 0   Download

Introduction: The plant Cannabis sativa L. has a long history for human being since about BC 2000 for its use as fiber material, food and folk medicine; cannabis (hemp, marijuana) means the whole plant itself and its dried products except for its stem and seeds. The word “hashish” is mainly used for the resin of the cannabis plant.

8p bigbaby87 01-09-2010 67 16   Download

Thus, in living cells, the rates of anterograde and retrograde transport between the two organelles appear to have a substantial effect on the morphology of the Golgi. The effect of the balance between anterograde and retrograde transport on the morphology of the ER remains to be explored. Recently, increasing evidence has suggested that alteration in Golgi morphology during mitosis is not a passive process but rather an active one, which is highly coordinated with entry into mitosis and its progression.

510p yeutinh98 22-09-2012 54 14   Download

The life cycle of the retrovirus consist of several steps. It begins with the binding of the viral envelope to cellular receptors, which enables fusion of the viral envelope with the cellular membrane. Consequently, the viral particle is uncoated, liberating the viral core into the cell cytoplasm. The viral DNA is reverse transcribed to DNA. Then, the viral DNA is transported to the nucleus where it is integrated into the host cell’s genome. From there, viral DNA is transcribed to RNA, some of which is translated to proteins.

602p kmkmkmkmkm 08-09-2012 31 12   Download

Acute haematogenous osteomyelitis refers to infection of bone resulting from bacteria in the bloodstream. This is seen most often in children, with initial infection thought to occur in the richly vascularised metaphyseal region (Gutierrez, 2005). Children are thought to experience frequent episodes of bacteraemia, often with no apparent symptoms, leading to seeding and development of osteomyelitis (Conrad, 2010). The pathogenesis of this process has been theoretically described.

306p wqwqwqwqwq 20-07-2012 42 8   Download

Các chất hoạt tính trong cần sa có thể làm giảm triệu chứng viêm sưng trong bệnh Bộ não. Alzheimer và do đó giúp ngăn ngừa sự suy thoái của hệ thần kinh. Hợp chất tổng hợp đó được gọi là cannabinoid. Các nhà khoa học đến từ Đại học Complutense ở Madrid và Viện nghiên cứu Cajal (Tây Ban Nha) đã ghi nhận được những tác dụng đầu tiên của cần sa đối với căn bệnh Alzheimer.

4p nkt_bibo26 20-12-2011 38 6   Download

The tax-exempt money market is more complex than the taxable money market. That’s largely because of a supply-and-demand imbalance for very short-term municipal securities. There’s a high level of demand for these issues—much of it coming from individuals who want to minimize their tax bill by placing their cash in a tax-exempt money market mutual fund. But supply is limited.

18p quaivatdo 18-11-2012 45 6   Download

In response to Texas’s affiliate rule, the federal Centers for Medicare and Medicaid Services (CMS) announced that it would no longer provide federal matching funds for the program because the rule denies beneficiaries the freedom to choose providers, as assured under federal policy and stated that the waiver and federal funding would terminate after six months. 4 Two lawsuits are now in progress as a result of these decisions.

11p connicquy 20-12-2012 32 5   Download

Le Centre de Développement des Ressources de la Terre (l'un des organismes scientifiques de l'Administration Britannique de Développement Outremer) apporte son aide aux pays en voie de développement en matière de cartographie, recherche et evaluation des ressources de la terre et fourni t des recommandations quant ä l'exploitation de ces ressources pour le développement de l'agriculture, l'élevage et la sylviculture.

29p thieubaotrang 23-04-2013 35 5   Download

The World Bank’s mission is to alleviate poverty and support sustainable development. The conservation and sustainable use of natural habitats and biodiversity will contribute to these goals by protecting ecosystem services that are critical to fulfilling these objectives. Biodiversity is the foundation and mainstay of agriculture, forests, and fisheries. Biological resources provide the raw materials for livelihoods, sustenance, medicines, trade, tourism, and industry.

7p yeurauxanh88 01-10-2012 33 4   Download