Cardiac function

To study the left ventricular myocardial function with two-dimensional speckle tracking echocardiography and the concordance of endocardial 2DSTE and coronary angiography on the localization of coronary artery stenosis.

7p vifaye 20-09-2024 1 1   Download

This study was carried out to evaluate the effect of Cobalt chloride (CoCl2) on cardiac mitochondrial function in an in vitro model. In the study, H9C2 cardiomyocytes were cultured in a medium containing different concentrations of CoCl2. Cell viability, cardiolipin content, mitochondrial function, and mitochondrial oxidative stress were assessed by using Cell Counting Kit-8 and suitable fluorescence kits.

6p guitaracoustic02 08-12-2021 5 2   Download

According to gene enrichment analysis, PPAR pathway, cardiac muscle contraction, and cytokinecytokine receptor interaction were the most enriched pathways. Besides, the nuclear factor-κB signaling pathway and hematopoietic cell linage pathways were also enriched. Chronic obstructive pulmonary disease (COPD) is enriched among KEGG disease pathways. RT-qPCR assays confirmed the RNA-Seq results. This study opens a new window toward the biological functions of Bex2 in different systems.

12p thiencuuchu 27-11-2021 16 1   Download

The aim study has been investigated: Investigated some parameters of morphology, left ventricular function and hemodynamic changes by using Doppler cardiac ultrasonography in normal pregnancy and pre-eclampsia. Find the relationship between the parameters of morphology, left ventricular function and hemodynamic changes and some clinical, subclinical characteristics with normal pregnancy and pre-eclampsia.

30p petsematary 02-06-2021 6 2   Download

To determine the prevalence, characteristics of hypertrophic cardiomyopathy and cardiac function in fetuses of diabetic mothers. To survey on some factors of mother and fetus related to fetal hypertrophic cardiomyopathy.

27p cothumenhmong6 17-07-2020 13 1   Download

Research objectives: Reviewing some clinical and subclinical symptoms, cardiac morphology and function via ultrasonography in cirrhotic patients; identifying a relationship between some parameters of cardiac morphology and function and some clinical and subclinical symptoms in cirrhotic patients.

30p change04 08-06-2016 43 2   Download

Cellular manifestations of aging are most pronounced in postmitotic cells, such as neurons and cardiac myocytes. Alterations of these cells, which are responsible for essential functions of brain and heart, are particularly important contributors to the overall aging process. Mitochondria and lysosomes of postmitotic cells suffer the most remarkable age-related alterations of all cellular organelles.

7p research12 01-06-2013 41 5   Download

There are at least three well-defined signalling cascades engaged directly in the physiological regulation of cardiac circulatory function: theb1-adrenoceptors that control the cardiac contractile apparatus,the renin-angiotensin-aldo-sterone system involved in regulating bloodpressure and the natriuretic peptides contributing at least to the factors determining circulating volume.

18p research12 29-04-2013 39 3   Download

Activation of a calcium-sensing receptor (Ca-SR) leads to increased intracellular calcium concentration and altered cellular activities. The expression of Ca-SR has been iden-tified in both nonexcitable and excitable cells, including neurons and smooth muscle cells. Whether Ca-SR was expressed and functioning in cardiac myocytes remained unclear. In the present study, the transcripts of Ca-SR were identified in rat heart tissues usingRT-PCRthat was further confirmed by sequence analysis.

9p fptmusic 16-04-2013 48 2   Download

We investigated structural and functional aspects of the first mutation in TNNC1, coding for the calcium-binding subunit (cTnC) of cardiac tropo-nin, which was detected in a patient with hypertrophic cardiomyopathy [Hoffmann B, Schmidt-Traub H, Perrot A, Osterziel KJ & Gessner R (2001) Hum Mut17, 524]. This mutation leads to a leucine–glutamine exchange at position 29 in the nonfunctional calcium-binding site of cTnC.

11p dell39 27-03-2013 50 5   Download

The existence of an inducible mitochondrial nitric oxide synthase has been recently related to the nitrosative⁄oxidative damage and mitochondrial dys-function that occurs during endotoxemia. Melatonin inhibits both inducible nitric oxide synthase and inducible mitochondrial nitric oxide synthase activities, a finding related to the antiseptic properties of the indoleamine.

13p galaxyss3 19-03-2013 35 3   Download

Voltage-gated potassium (KV) channels can form heteromultimeric com-plexes with a variety of accessory subunits, including KCNE proteins. Het-erologous expression studies have demonstrated diverse functional effects of KCNE subunits on several KV channels, including KCNQ1 (KV7.1) that, together with KCNE1, generates the slow-delayed rectifier current (IKs) important for cardiac repolarization.

14p media19 06-03-2013 28 2   Download

Angiotensin-converting enzyme (ACE) and its homologue angiotensin-converting enzyme 2 (ACE2) are critical counter-regulatory enzymes of the renin–angiotensin system, and have been implicated in cardiac function, renal disease, diabetes, atherosclerosis and acute lung injury.

10p vinaphone15 28-02-2013 39 3   Download

A multiprotein complex encompassing a transcription regulator, cardiac ankyrin repeat protein (CARP), and the calpain 3 protease was identified in the N2A elastic region of the giant sarcomeric protein titin. The present study aimed to investigate the function(s) of this complex in the skeletal muscle. We demonstrate that CARP subcellular localization is controlled by the activity of calpain 3: the higher the calpain 3, the more important the sarcomeric retention of CARP.

16p viettel02 19-02-2013 40 4   Download

The cardiac hormones atrial natriuretic peptide and B-type natriuretic pep-tide (brain natriuretic peptide) activate guanylyl cyclase (GC)-A⁄natriuretic peptide receptor-A (NPRA) and produce the second messenger cGMP. GC-A⁄NPRA is a member of the growing family of GC receptors.

16p cosis54 05-01-2013 34 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Inhibition of neutrophil activity improves cardiac function after cardiopulmonary bypass...

9p thulanh27 13-12-2011 53 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Endothelial Cardiac filling volumes versus pressures for predicting fluid responsiveness after cardiovascular surgery: the role of systolic cardiac function...

11p thulanh18 05-11-2011 52 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Transpulmonary thermodilution-derived cardiac function index identifies cardiac dysfunction in acute heart failure and septic patients: an observational study...

10p coxanh_6 29-10-2011 42 3   Download

Available online http://ccforum.com/content/12/4/R101 Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients...

13p coxanh_3 27-10-2011 48 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Clinical investigation: thyroid function test abnormalities in cardiac arrest associated with acute coronary syndrome...

9p coxanh_2 24-10-2011 50 3   Download