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Cell death following

Xem 1-20 trên 81 kết quả Cell death following
  • Synthetic indolyl- pyridinyl- propenones (IPPs) induce methuosis, a form of non-apoptotic cell death, in glioblastoma and other cancer cell lines. Methuosis is characterized by accumulation of cytoplasmic vacuoles derived from macropinosomes and late endosomes, followed by metabolic failure and rupture of the plasma membrane.

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  • There has been interest in the potential benefit of vitamin D (VD) to improve breast cancer outcomes. Pre-clinical studies suggest VD enhances chemotherapy-induced cell death.

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  • Successful treatment of oesophageal cancer is hampered by recurrent drug resistant disease. We have previously demonstrated the importance of apoptosis and autophagy for the recovery of oesophageal cancer cells following drug treatment.

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  • Carbohydrates are sugars and starches derived from cereals, tubers, roots, and other substances such as cellulose and lignin from plant cell walls, vessels and woody tissues. Carbohydrates do mainly provide energy for maintenance and production. A surplus of energy is stored as body fat. A part of the carbohydrates is crude fibre (CF), the remaining is nitrogen-free extract (NFE). The latter consists of sugars, starches and sugar-like substances. Sugars and starches are much easier to digest than CF.

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  • Automatic sampler (optional)—The sampler must incorporate glass sample containers for the collection of a minimum of 250 mL of sample. Sample containers must be kept refrigerated at 4°C and protected from light during compositing. If the sampler uses a peristaltic pump, a minimum length of compressible silicone rubber tubing may be used. Before use, however, the compressible tubing should be thoroughly rinsed with methanol, followed by repeated rinsings with distilled water to minimize the potential for contamination of the sample.

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  • About half of all deaths from unsafe abortion are in Asia, with most of the remainder (44%) in Africa. 6 The unsafe abortion mortality ratio (the number of unsafe abortion-related deaths per 100 000 livebirths) varies across regions. For the developing world as a whole, this ratio was estimated to be 60 in the year 2000. However, the ratio is much higher in eastern, middle, and western Africa (90–140), and is lower in northern and southern Africa, western and southeastern Asia, and Latin America and the Caribbean (10–40).

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  • This paper presents SIENA, an event notification service that we have de- signed and implemented to maximize both expressiveness and scalability. In Section 3we describe the service’s formally defined application programming in- terface,which is an extension of the familiar publish/subscribe protocol [Birman 1993]. Several candidate server topologies and protocols are presented in Sec- tion 4.

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  • The leading features content is very vaguely considered in the reports. Material selection and second extent configurations (e.g. texture, colour and light) can best identify the answer to question A. For example, the content is described as follows: “door handle should be made in aluminium and polished to a glossy smooth surface without texture, to convey the cold, cynical, military-industrial terms”. The structural principle for the door handle is its function as a tool for twisting and pulling, and for a computer mouse a resting hand shape.

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  • Following a brief overview of the state of the evidence regarding household energy interventions, indoor air pollution and health, the presentation "Why evaluate?" describes multiple evaluation perspectives. Target audiences and purposes for evaluation can range from informing the community that their needs and concerns have been addressed to contributing to the international evidence base by carefully documenting intervention impacts. Moreover, data on the costs and benefits of an intervention project or programme can feed into economic evaluation.

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  • This is the "income effect". 13 In his well- known work Becker (1981) argued however that if the increase in household income were due to an increase in wage rates (i.e., an increase in labour productivity), the cost of children would increase, because time is involved in producing and rearing them. But other things being the same, this would lead to a decrease in the demand for children (this is the "substitution effect").

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  • This contribution is organised in the following manner - the first section is devoted to the development of Proudhon’s thought in relation to speculation. It is divided into two parts. The first part is dedicated to Pierre-Joseph Proudhon’s definitions of stock market speculation or gambling with shares that for him served no purpose either from a human or economic perspective and was therefore condemnable and to be contrasted with entrepreneurial speculation that, even though it is a highly-risky activity, involves the spirit of enterprise and provides the lifeblood of economic growth.

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  • Delimiting word boundaries in a speech stream is no easier than trying to determine them in the previous paragraph. So how do young infants crack the sound code? They perform frequency analyses. Take for example the sound sequence What a pretty baby you are.

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  • In the time it takes you to make just one in-person sales call, you could stay at your office, pick up the telephone, and potentially reach dozens, if not hundreds, of potential prospects, using basic outbound telemarketing efforts.

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  • A number of developments have inadvertently exposed the extent to which the accountancy profession had become a major industry and, thus, indirectly invited critical reflection upon the relevance and adequacy of its regulation. Consideration of the three episodes allows us to explore how accountants have responded to the challenge of change and, more specifically, how they have sought to address and neutralise the threat to the image of themselves (and associated material benefits) as responsible, independent professionals.

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  • In the second study an attempt was made to determine whether there might be a relationship between reproductive messages and the popularity/sales of recorded contemporary songs. This was accomplished by measuring the number of reproductive messages in 30 randomly selected songs from each of the three charts that made it into the Top Ten in 2009 and also appeared in albums. As a control condition, we measured the number of reproductive messages in randomly selected songs from the same album by the same vocalists that did not make it into the Top 10. As a result, each...

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  • Our first order of business is to make certain that we are a good fit to work together. Part of that assessment will be a candid discussion about your expectations and goals. If the goals, or the timeframe for their achievement are unreasonable and depend too much on lucky breaks and good fortune, IdeaBridge will politely pass on the opportunity. We’ve worked extremely hard to build a stellar reputation for consistent results, and therefore will not accept projects or assignments from any group that has unrealistic expectations. If nothing else, we can help ground you in...

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  • I am particularly indebted to Drs Graça Loureiro, Beatriz Tavares, Daniel Machado and Prof A Segorbe Luís, from Immunoallergy Departement of Coimbra University Hospital Center who willingly assisted me in the review and in the scientific discussion of some fundamental aspects that have benefited the final version. The preparation of this edition for publication depends heavily on the excellent professional secretarial work of Ms Molly Kaliman, Publishing Process Manager. Of course a special thanks to the Intech-Open Access Publisher who had honored me with that feat challenge.

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  • In the middle of the 20th century, we saw our planet from space for the first time. Historians may eventually find that this vision had a greater impact on thought than did the Copernican revolution of the 16th century, which upset the human self-image by revealing that the Earth is not the centre of the universe. From space, we see a small and fragile ball dominated not by human activity and edifice but by a pattern of clouds, oceans, greenery, and soils. Humanity's inability to fit its activities into that pattern is changing planetary systems, fundamentally.

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  • While a significant number of nations have adopted or accepted IFRS, in order to achieve the true benefits of a uniform set of accounting standards, it is important that IFRS is adopted by nations in a manner consistent with those issued by the IASB. In addition, it is equally important that they are applied and enforced in a consistent manner. Therefore, there must also be a mechanism to ensure that auditing standards and the practices of auditors facilitate consistent application of IFRS. Similarly, over time there must be improved coordination of global regulatory review.

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  • A real example of this principle is the use of the “commander’s intent” in the U.S. Army. The Army knows that its leaders cannot be everywhere in the field of combat controlling all the decisions. Therefore, Army leaders clearly establish the “commander’s intent” to serve as a guide on which soldiers can base their own initiatives, actions and decisions. Thus, even if the mission falls on the shoulders of the lowest ranking person, she must be able to understand and carry out the mission. Likewise, you, the agile manager, can guide the team and continuously influence team...

    pdf7p tay_thi_le 21-02-2013 56 5   Download

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