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Chromosome damage
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In the study of Pang et al. (2018) uses a scatter simulated annealing algorithm to minimize the total delay and total turnaround time for bi-objective PM scheduling problems at a station [13]. Also, Lin et al. (2019), consider many chromosomes in genetic algorithms to obtain the best PM scheduling.
6p
longtimenosee06
27-03-2024
2
2
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Genomic alterations, including loss of function in chromosome band 11q22-23, are frequently observed in neuroblastoma, which is the most common extracranial childhood tumour. In neuroblastoma, ATM, a DNA damage response-associated gene located on 11q22-23, has been linked to tumorigenicity.
13p
vischultz
20-10-2023
2
1
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Accumulation of DNA damage, mutations, and chromosomal abnormalities is associated with aging in many organisms. How directly various forms of genomic instability contribute to lifespan in different aging contexts is still under active investigation.
15p
vinarcissa
21-03-2023
5
1
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Structural maintenance of chromosomes (SMC) complexes are central organizers of chromatin architecture throughout the cell cycle. The SMC family member condensin is best known for establishing long-range chromatin interactions in mitosis. These compact chromatin and create mechanically stable chromosomes.
25p
viarchimedes
26-01-2022
5
0
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Quantitative detection of histone modifications has emerged in the recent years as a major means for understanding such biological processes as chromosome packaging, transcriptional activation, and DNA damage.
13p
visilicon2711
20-08-2021
8
2
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Pre-harvest sprouting (PHS) in wheat can cause severe damage to both grain yield and quality. Resistance to PHS is a quantitative trait controlled by many genes located across all 21 wheat chromosomes.
14p
vijichea2711
28-05-2021
10
1
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Targeting Protein for Xenopus Kinesin Like Protein 2 (TPX2) is a microtubule associated protein that functions in mitotic spindle assembly. TPX2 also localizes to the nucleus where it functions in DNA damage repair during S-phase.
11p
vianrose2711
27-04-2021
6
2
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Chromosomal inversions involving anaplastic lymphoma kinase (ALK) and echinoderm microtubule associated protein like 4 (EML4) generate a fusion protein EML4-ALK in non-small cell lung cancer (NSCLC). The understanding of EML4-ALK function can be improved by a functional study using normal human cells.
16p
vianrose2711
27-04-2021
13
1
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Concurrent cisplatin radiotherapy (CCRT) is a current standard-of-care for locally advanced head and neck squamous cell carcinoma (HNSCC). However, CCRT is frequently ineffective in patients with advanced disease.
13p
vimale2711
21-08-2020
10
1
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BRCA1 and BRCA2 mutations explain approximately one-fifth of the inherited susceptibility in high-risk Finnish hereditary breast and ovarian cancer (HBOC) families. EMSY is located in the breast cancerassociated chromosomal region 11q13.
8p
vidhaka2711
31-07-2020
10
1
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Survivin, belonging to the inhibitor of apoptosis (IAP) gene family, is abundantly expressed in tumors. It has been hypothesized that Survivin facilitates carcinogenesis by inhibition of apoptosis resulting in improved survival of tumorigenic progeny.
17p
vibaku2711
22-07-2020
11
1
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Chromosomal rearrangements are the typical phenomena in cancer genomes causing gene disruptions and fusions, corruption of regulatory elements, damage to chromosome integrity.
17p
vikuala271
13-06-2020
8
0
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Aflatoxin B1 (AFB1) is a widespread mycotoxin produced by toxicogenic Aspergillus species. AFB1 has been reported to cause harmful health effects, such as cancers and abnormal development and reproduction, in animals and humans. The current study was carried out to evaluate the genotoxic aspects of Aflatoxin B1 in the bone marrow cells obtained from Swiss albino mice, using chromosomal aberrations (CA), mitotic index (MI), and micronuclei (MN) formation as toxicological end points.
9p
kethamoi4
18-04-2020
12
2
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Numerous studies have identified specific body systems affected by the hazardous effects of the cigarette smoking particularly the respiratory and cardiovascular systems. The effect of smoking on male reproduction has also been studied where semen quality was investigated in different cross-sectional studies including infertile patients with conflicting results. This article aimed to assess the relationship between smoking and male infertility.
8p
kethamoi1
20-11-2019
14
1
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Drought and salinity induce biochemical, physiological, morphological, and genetic responses in plants. To understand the damage to different wheat species caused by these stresses, we investigated root-shoot growth, cell division, chromosomal aberrations and nucleolus organizer regions (AgNORs) in root tip cells.
9p
sony2711
28-01-2019
28
2
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Teucrium species have been used in traditional medicine for treatment of different diseases. The aim of this study was to investigate polyphenolic contents by high-performance liquid chromatography (HPLC), and the genotoxic effect of methanolic extracts of Teucrium polium and Teucrium scordium using the cytokinesis-block micronucleus (CBMN) assay on human peripheral blood lymphocytes (PBLs) from healthy donors.
11p
nutifooddau
27-01-2019
38
1
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(bq) part 1 book “radiobiology for the radiologist” has contents: physics and chemistry of radiation absorption, molecular mechanisms of dna and chromosome damage and repair, cell survival curves, radiosensitivity and cell age in the mitotic cycle, fractionated radiation and the dose-rate effect,… and other contents.
475p
dien_vi09
13-10-2018
20
2
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No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials, instructions,
148p
donghanhmuathi
04-05-2013
38
2
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The production of free radicals (ROS) is an unavoidable consequence of life in an aerobic environment. Free radicals produced from the metabolic activities of oxygen attack biological membranes and lipoproteins via oxidation in a process called lipid perioxidation. This attack damages cells and lipids often in a chain reaction with carbon-based molecules such as polyunsaturated fatty acids (PUFA) in a reaction with molecular oxygen. This creates oxidative stress and damage to tissues. Free radicals also damage chromosomal DNA.
272p
mnemosyne75
02-02-2013
63
12
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Understanding the biological basis of aging has fascinated people throughout recorded history, and is one of the great remaining scientific questions. The question has never been more important than now, as we anticipate the impact that a rapidly growing older population will have on the social, political, and medical landscape over the next 50 years. There is increasing evidence that aging involves damage to the genome, and it is certainly the case that such damage explains much of the coupling of most cancers to aging.
598p
hyperion75
18-01-2013
48
8
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