Chronic inflammatory disease

Regulator of G-protein signaling (RGS) proteins were originally identified as negative regulators of G-protein-coupled receptor (GPCR) signaling via their GTPase-accelerating protein (GAP) activity. All RGS proteins contain evolutionarily conserved RGS domain; however, they differ in their size and regulatory domains. RGS1 and RGS10 are smaller than other RGS proteins, and their functions involve various inflammatory responses including autoimmune responses in both the periphery and the central nervous system (CNS). Neuroinflammation is the chronic inflammatory response in the CNS.

5p caothientrangnguyen 09-05-2020 28 2   Download

Rheumatoid arthritis (RA) is a systemic, chronic inflammatory disease that affects 0.5–1% of the population. RA causes progressive joint destruction that leads to the restriction of activities of daily living and deterioration of quality of life.

7p galaxyss3 07-03-2013 32 3   Download

Obesity is a low-grade chronic inflammatory disease associated with an increased number of macrophages (adipose tissue macrophages) in adipose tissue. Within the adipose tissue, adipose tissue macrophages are the major source of visfatin⁄pre-B-cell colony-enhancing factor⁄nicotinamide phos-phoribosyl transferase.

13p viettel02 19-02-2013 39 3   Download

Background: Dercum’s disease (DD) is characterised by obesity and chronic pain ( 3 months) in the adipose tissue. The pathogenesis of DD is unknown, but inflammatory components have been proposed. In previous reports and studies, an inconsistent picture of the histological appearance of the adipose tissue in DD has been described. The aim of this investigation was to examine the histological appearance of adipose tissue in patients with DD, with particular focus on inflammatory signs. Methods: Fat biopsies were sampled from painful regions from 53 patients with DD.

6p thulanh27 12-12-2011 65 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Chronic granulomatous disease: a review of the infectious and inflammatory complications...

14p coxanh_5 28-10-2011 45 4   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Chronic Obstructive Pulmonary Disease, inflammation and co-morbidity – a common inflammatory phenotype...

9p toshiba13 21-10-2011 52 4   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study...

14p toshiba12 21-10-2011 46 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Active immunization to tumor necrosis factor-α is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis...

10p thulanh14 19-10-2011 50 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: The potential of human regulatory T cells generated ex vivo as a treatment for lupus and other chronic inflammatory diseases...

6p thulanh12 12-10-2011 39 4   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease...

14p thulanh11 11-10-2011 38 3   Download

FDA cho phép dùng thuốc mới Remicade (infliximab) cho việc điều trị bệnh viêm ruột Crohn’s disease. Remicade là một loại thuốc do điều chế kháng thể đơn dòng (monoclonal antibody). Thuốc giảm hiện tượng viêm bằng cách ngăn chặn yếu tố tumor necrosis factor-alpha (TNF-alpha). FDA Approves Remicade for Children with Crohn’s Disease The Food and Drug Administration today approved Remicade (infliximab) to treat children with active Crohn's disease, a chronic, inflammatory condition of the bowel that can be severely debilitating.

7p nganluong111 14-04-2011 105 5   Download

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease primarily of the joints that, if lelt untreated, results in functional disebility concordant with radiographic progression. It is well recognized that strking pathogenic similarities exist between periodontitis and RA. Proinflammatory cytokines such as tumor necrosis factoralpha (TNF a) and interleukin (IL) as well as microbial enzymes and host matrix metalloproteianses (MMP-8 and -9) appear to play important roles in both conditions....

11p mongmo_tc12c 28-10-2010 107 4   Download