Clinical determinants
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Clinical and genetic characteristics of children with Alagille syndrome in Children’s Hospital No. 1
Alagille syndrome is an autosomal dominant disorder that affects many various organs. Objectives: Determining the prevalence of clinical and genetic characteristics of children with Alagille syndrome in Children’s Hospital No.1.
7p viwalton 29-06-2024 1 1 Download
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5-Fluorouracil (5FU) is a primary chemotherapeutic agent used to treat oral squamous cell carcinoma (OSCC). However, the development of drug resistance has significantly limited its clinical application. Therefore, there is an urgent need to determine the mechanisms underlying drug resistance and identify effective targets.
16p vishanshan 27-06-2024 2 1 Download
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Determination of drug-related problems in the hematology service: A prospective interventional study
Patients with hematological malignancies often require multidrug therapy using a variety of antineoplastic agents and supportive care medications. This increases the risk of drug-related problems (DRPs). Determining DRPs in patients hospitalized in hematology services is important for patients to achieve their drug treatment goals and prevent adverse effects.
8p vishanshan 27-06-2024 2 1 Download
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KRAS is the undisputed champion of oncogenes, and despite its prominent role in oncogenesis as mutated gene, KRAS mutation appears infrequent in gliomas. Nevertheless, gliomas are considered KRAS-driven cancers due to its essential role in mouse malignant gliomagenesis. Glioblastoma is the most lethal primary brain tumor, often associated with disturbed RAS signaling.
11p vishanshan 27-06-2024 1 1 Download
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This systematic review and meta-analysis aimed to determine the potential value of neutrophil to lymphocyte ratio (NLR) as an assessment tool in the clinical distinction between uterine sarcoma and uterine leiomyoma.
9p vishanshan 27-06-2024 1 1 Download
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Taxanes appear to be safe following the first trimester of pregnancy, with obstetric and fetal outcomes being similar to those observed in the general obstetric population. Future studies should aim to determine the most effective taxane regimen and dosage for use during gestation, with a specific focus on treatment safety.
8p vishanshan 27-06-2024 1 1 Download
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The relationship between work and health is complex and bidirectional, where work can have both health-harming and health-enhancing effects. Though employment is recognized as a social determinants of health, and clinical healthcare delivery systems are increasingly using screening tools to ask patients about social needs, little research has explored the extent to which employment-related social risk is captured in these screening tools.
10p vishanshan 27-06-2024 2 1 Download
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Access to culturally safe and responsive services can be improved by engaging Aboriginal and Torres Strait Islander Health Workers and similar roles in an online community of practice, supporting the integration of cultural and clinical knowledge and self-determination of Aboriginal and Torres Strait Islander consumers in decisions affecting their health.
13p vishanshan 27-06-2024 2 1 Download
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Determine the rate of Autism Spectrum Disorder in children between the ages of 18 and 36 months by utilizing the M-CHAT-R scale at the clinic of Can Tho Children's Hospital. And identify the associated risk factors for that rate of Autism Spectrum Disorder.
8p vikoch 27-06-2024 1 1 Download
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Selective lateral pelvic lymph node (LPN) dissection (LPND) following neoadjuvant chemoradiotherapy (nCRT) for rectal cancer is widely recognized. This study aimed to determine the effects of nCRT before LPND on local control and prognosis of rectal cancer patients.
10p vikoch 27-06-2024 2 1 Download
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Part 1 book "Small animal cardiovascular medicine" includes content: Cardiac embryology and anatomy; normal clinical cardiovascular physiology; signalment, history, and physical examination; radiography of the cardiovascular system; electrocardiography; echocardiography; cardiac catheterization; classification of heart disease by echocardiographic determination of functional status - classification of heart disease by echocardiographic determination of functional status, pathophysiology of heart failure, management of heart failure.
658p dianmotminh03 17-06-2024 0 0 Download
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To determine the correlation between clinical symptoms, computer tomography scan (CT-scan), and histopathologic findings of chronic rhinosinusitis (CRS). Methods: A prospective, case-by-case study on 33 patients with CRS who were diagnosed and treated by functional endoscopic sinus surgery at the Department of Otolaryngology, Military Hospital 103 from January 2022 to August 2022.
9p vijaychest 16-05-2024 3 1 Download
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To determine mortality characteristics of multiple trauma patients who were treated at Military Hospital 103. Methods: A prospective, descriptive study on 196 multiple trauma patients who were admitted and treated at the Surgical Intensive Care Unit (SICU), Military Hospital 103. Patients' clinical and subclinical data were collected at the time of admission, during treatment, and at the time of discharge from the SICU.
10p vijaychest 16-05-2024 3 1 Download
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In this study, all the expressions of Otubain-1, NF-κB2, SHPs and STATs genes, the concentrations of cytokines IL-1β, IL-6 and TNF-α and clinical features in NHL patients were examined. To the end, gene expression levels of 82 NHL patients and 56 healthy individuals were determined by quantitative real time RT-PCR and secretion of cytokines by ELISA.
10p dianmotminh02 03-05-2024 5 1 Download
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Ebook "The new paradigm of immunity to tuberculosis" illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former’s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed.
294p ladongphongthanh1008 22-04-2024 7 2 Download
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In ebook "Developmental biology of neoplastic growth" tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest.
263p tracanhphuonghoa1007 22-04-2024 4 2 Download
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Nursing home residents have increased rates of intestinal colonisation with multidrug-resistant organisms (MDROs). We assessed the colonisation and spread of MDROs among this population, determined clinical risk factors for MDRO colonisation and investigated the role of the gut microbiota in providing colonisation resistance against MDROs.
17p vibransone 28-03-2024 4 1 Download
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High-grade serous tubo-ovarian cancer (HGSTOC) is characterised by extensive inter- and intratumour heterogeneity, resulting in persistent therapeutic resistance and poor disease outcome. Molecular subtype classification based on bulk RNA sequencing facilitates a more accurate characterisation of this heterogeneity, but the lack of strong prognostic or predictive correlations with these subtypes currently hinders their clinical implementation.
30p vibransone 28-03-2024 6 2 Download
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Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis
Rapid advances in the past decade have shown that dysbiosis of the gut microbiome is a key hallmark of rheumatoid arthritis (RA). Yet, the relationship between the gut microbiome and clinical improvement in RA disease activity remains unclear.
20p vibransone 28-03-2024 1 1 Download
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The study aimed to determine the smoking prevalence and explore the association between smoking and viral load among people living with HIV who are drug users (HIV+ PWID) in Vietnam. We used secondary data from a descriptive cross-sectional study of 280 HIV+ PWID in an open-label, non-inferiority trial from July 2015 to February 2018 at six HIV clinics in Northern Vietnam.
10p vilarry 12-03-2024 4 1 Download