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Consensus structure

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  • The thesis is structured as follows: Chapter 1 introduction; chapter 2 a review of fuzzy multicriteria analysis approaches; chapter 3 problem formulation and developments; chapter 4 pairwise comparison based multicriteria decision making under uncertainty; chapter 5 effective decision support for fuzzy multicriteria group decision making; chapter 6 a consensus based approach for multicriteria group decision making; chapter 7 risk-oriented decision making for multicriteria group decision making under uncertainty; chapter 8 hospital location evaluation and selection under uncertainty; chapter...

    pdf232p runthenight04 02-02-2023 5 2   Download

  • A structured approach to perioperative patient management based on an enhanced recovery pathway protocol facilitates early recovery and reduces morbidity in high income countries. However, in low- and middle-income countries (LMICs), the feasibility of implementing enhanced recovery pathways and its influence on patient outcomes is scarcely investigated.

    pdf6p vitennessee2711 01-02-2021 8 1   Download

  • RNAalifold, a popular computational method for RNA consensus structure prediction, incorporates covarying mutations into a thermodynamic model to fold the aligned RNA sequences. When quantifying covariance, it evaluates conserved signals of two aligned columns with base-pairing rules.

    pdf10p viwyoming2711 16-12-2020 10 1   Download

  • Terminal restriction fragment length polymorphism (T-RFLP) analysis is a common DNA-fingerprinting technique used for comparisons of complex microbial communities. Although the technique is well established there is no consensus on how to treat T-RFLP data to achieve the highest possible accuracy and reproducibility.

    pdf18p vikentucky2711 26-11-2020 8 0   Download

  • Evolutionary variations let us define a set of similar nucleic acid sequences as a family if these different molecules execute a common function. Capturing their sequence variation by using e. g. position specific scoring matrices significantly improves sensitivity of detection tools.

    pdf17p vikentucky2711 24-11-2020 9 1   Download

  • The cyclin-dependent kinase 2 (CDK2) together with its cyclin E and A partners is a central regulator of cell growth and division. Deregulation of CDK2 activity is associated with diseases such as cancer. The analysis of substrates identified S/T-P-X-R/K/H as the CDK2 consensus sequence.

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  • Analysis of gene expression data provides valuable insights into disease mechanism. Investigating relationship among co-expression modules of different stages is a meaningful tool to understand the way in which a disease progresses. Identifying topological preservation of modular structure also contributes to that understanding.

    pdf23p vioklahoma2711 19-11-2020 13 0   Download

  • Soil biochemical properties are indicators of soil quality, but there is still no consensus as to how they should be used. Generally, biochemical properties related to the biocycles of the elements (C, N, P and S) are used to diagnose soil quality. These properties include both general biochemical parameters (i.e. microbial biomass C, dehydrogenase activity and N mineralization potential) and specific biochemical parameters (i.e. the activity of hydrolytic enzymes, such as phosphatase, Dehydrogenase, urease and b-glucosidase).

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  • Globalization has forced many countries to rely on one another for products and services which they are unable to source locally. More so, trade is used as the channel to procure those. South Africa and China share very close relations which are boosted by South Africa’s neo-liberal policy, and its membership of the BRICS bloc. Often, this relationship has been subjected to different interpretations leading to the inability to reach a consensus on South Africa’s intention and exact benefits from neo-liberalization and membership of BRICS bloc.

    pdf8p chauchaungayxua2 09-01-2020 26 1   Download

  • There is wide consensus that ongoing deforestation contributes to global warming and poses a threat to species diversity. Less understood is whether the practice of creating plantations might also erode genetic diversity and undermine the genetic structure of tree populations.

    pdf14p vimb123 11-01-2019 37 2   Download

  • In the last decades scientists around the world have come to a consensus that the survival of humanity is threatened by rising climate changes if people continue to consume and produce in the same way as it has been. According to different analyses including those commissioned by the World Bank, Vietnam is among the countries to be heavily impacted by a rise in sea level caused by the melt of Northern and Southern ice caps.

    pdf20p danhnguyentuongvi27 18-12-2018 25 1   Download

  • DNA cytosine methyltransferaseMspI(M.MspI) must require a different type of interaction of protein with DNA from other bacterial DNA cytosine methyltransferases (m5C-MTases) to evoke the topoisomerase activity that it possesses in addition toDNA-methylation ability. Thismay require a different structural organization in the solution phase from the reported consensus structural arrangement for m5C-MTases.

    pdf7p research12 29-04-2013 44 2   Download

  • Domain IV, consisting of about 230 residues, represents a particular protein module so far found only in lamininb1 andb2 chains. Both domains were obtained by recombi-nant production in mammalian cells. They showed a globular structure, as expected from electron microscopic examination of laminins. Fragmentb1IV was obtained as a monomer and a disul®de-bonded dimer, and both were modi®ed to50% by a single chondroitin sulfate chain attached to Ser721 of an SGD consensus sequence.

    pdf12p research12 23-04-2013 40 1   Download

  • These pest infestations are infrequent and typically limited to breeding flocks or layers. Broilers and market turkeys are seldom if ever affected. Management of ectoparasites largely consists of whole flock treatments whenever infestations are detected by scouting birds and/or inspection of the structure and equipment (nest boxes, curtains, slats, cages). Other effective management techniques are not available. It is estimated that slightly more than 4 percent of breeder birds and layers are treated for ectoparasites each year.

    pdf17p loginnhanh 22-04-2013 52 1   Download

  • Limitedproteolysis of the pyruvate decarboxylase (E1,a2b2 ) component of the pyruvate dehydrogenase (PDH) multi-enzyme complexofBacillus stearothermophilushas indicated the importance for catalysis of a site (Tyr281-Arg282) in the E1asubunit (Chauhan, H.J., Domingo, G.J., Jung, H.-I. & Perham, R.N. (2000)Eur. J. Biochem.267, 7158–7169). This site appears to be conserved in the a-subunit of hetero-tetrameric E1s and multiple sequence alignments suggest that there are additional conserved amino-acid residues in this region, part of a common pattern with the consensus sequence -YR-H-D-YR-DE-.

    pdf10p tumor12 20-04-2013 52 2   Download

  • Certain spans of utterances in a discourse, referred to here as segments, are widely assumedto form coherent units. Further, the segmental structure of discourse has been claimed to constrain and be constrained by many phenomena. However, there is weak consensus on the nature of segments and the criteria for recognizing or generating them. We present quantitative results of a two part study using a corpus of spontaneous, narrative monologues. The first part evaluates the statistical reliability of human segmentation of our corpus, where speaker intention is the segmentation criterion. ...

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  • CD40 is areceptorwithnumerous functions in theactivation of antigenpresentingcells (APCs), particularlydendritic cells (DC). Using phage display technology, we identified linear peptides containing a novel FPGN/S consensus sequence that enhances the binding of phage to a purified murine CD40-immunoglobulin (Ig) fusion protein (CD40-Ig), but not to Ig alone. To examine the ability theFPGN/Speptides to enhance adenoviral infection of CD40-positive cells, we used bifunctional peptides consisting of an FPGN-contain-ing peptide covalently linked to an adenoviral knob-binding peptide (KBP)....

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  • In this paper, we address the issue for learning better translation consensus in machine translation (MT) research, and explore the search of translation consensus from similar, rather than the same, source sentences or their spans. Unlike previous work on this topic, we formulate the problem as structured labeling over a much smaller graph, and we propose a novel structured label propagation for the task.

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  • ATP-dependent Lon proteases belong to the superfamily of AAA + proteins. Until recently, the identity of the residues involved in their proteolytic active sites was not elucidated. However, the putative catalytic Ser–Lys dyad was recently suggested through sequence comparison of more than 100 Lon proteases from various sources. The presence of the catalytic dyadwas experimentally confirmedby site-directed mutagenesis of theEscherichia coliLon protease and by determination of the crystal structure of its proteolytic domain.

    pdf0p awards 05-04-2013 34 1   Download

  • We used a combined computer and biochemical approach to characterize human pyridoxine 5¢-phosphate oxidase (PNPO).The human PNPOgene is composed of seven exons and six introns, and spans approximately 8 kb.All exon/intron junctions contain the gt/ag consensus splicing site.The absence of TATA-like sequences, the presence of Sp1-binding sites and more importantly, the presence of CpG islands in the regulatory region of thePNPOgene are characteristic features of housekeeping genes.

    pdf10p dell39 03-04-2013 46 2   Download

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