Considerations for successful

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  • The discovery of efficacious new human therapeutic agents is one of humanity’s most vital tasks. It is an enormously demanding activity that requires creativity, a vast range of scientific knowledge, and great persistence. It is also an exceedingly expensive activity. In an ideal world, no education would be complete without some exposure to the ways in which new medicines are discovered and developed. For those young people interested in science or medicine, such knowledge is arguably mandatory....

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  • Natural products are a constant source of potentially active compounds for the treatment of various disorders. The Middle East and tropical regions are believed to have the richest supplies of natural products in the world. Plant derived secondary metabolites have been used by humans to treat acute infections, health disorders and chronic illness for tens of thousands of years. Only during the last 100 years have natural products been largely replaced by synthetic drugs.

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  • The contraction of the ABCP market suggests an explanation for why bank balance sheets have not (so far) contracted as sharply as they did in 1998. The beginnings of the credit problems of 2007 were fi rst manifested by falling prices of securities that are associated with the subprime sector. For instance, the ABX indices started to fall in June of 2007. The ABX indices track the credit default swaps (CDS) associated with various rated tranches of collateralized debt obligations (CDOs) written on subprime mortgages, and are compiled by the London fi rm Markit.

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  • The Japanese residential fuel cell scheme accounts for the majority of shipments in this application, under the Ene-Farm brand. By 2010, it was clear that the scheme was well on its way to being a success, delivering signifi cant cost reductions and performance improvements and allowing subsidies to come down, and by the end of the year fuel cell heating and power had been brought to over 13,500 households in total. Good growth in sales was expected in 2011, but what no one could have anticipated were the events of March 2011, when the T¯ ohoku earthquake and tsunami struck...

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  • While coding and signal processing are key elements to successful implementation of a MIMO system, the communication channel represents a major component that determines system performance. A considerable volume of work has been performed to characterize communication channels for general wireless applications. However, because MIMO systems operate at an unprecedented level of complexity to exploit the channel space-time resources, a new level of understanding of the channel space-time characteristics is required to assess the potential performance of practical multiantenna links....

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  • Emergency Planning is a critical component of every facility’s mission to provide a safe environment for its residents, staff, patrons and visitors. The key to successful emergency response lies in the details of preparedness. Generic (one-size fits all) guidelines for emergency response are insufficient. Our safety in an emergency depends on the careful, detailed planning and training that goes on well before an emergency occurs and that is specific to each facility.

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  • Resources are more than the human element. They consist of all things necessary for you to accomplish your goals. There are at least ten items for consideration when building a resources plan.

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  • for Scottish Aquaculture, 2003). This success story has been accompanied by growing concern over the environmental impact and sustainability of the industry. This has mainly been based around the localised impact upon the production sites, concern over the impact upon wild salmon and sea trout stocks as well as wider ecosystem effects. One of the factors considered in the latter category is the need for considerable volumes of fish meal and fish oil in carnivorous fin fish diets.

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  • Success with Facebook applications is one part idea, one part technical, and one part execution. Mike’s book does an amazing job covering all three. He takes you from evaluating your idea and thinking about platform strategy through every step of building the application and then even covers advanced strategies and considerations for scaling. This book will save you a tremendous amount of time learning the platform and building a successful viral application.

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  • The European market presents service providers with some unique challenges in pushing fiber closer to the end user. With virtually no overhead distribution and very little buried fiber cable, a new physical plant is unlikely. Rather, service providers are seeking the best way to use existing ducted infrastructure—and network planners must be willing to consider what architectures will best serve their needs today and in the foreseeable future.

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  • In open or laparoscopic radical prostatectomy, residual cancer relates with PSA failure. RTURPCa is probably less invasive than radical prostatectomy and more flexible in the point that the second operation can be indicated and easily done to eliminate residual cancer when PSA shows a successive rise. The second RTUR-PCa was required in 46 patients. But this is considered just a technical issue because the need for the second operation has decreased as the surgeon has become experienced.

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  • When the groundwork for the fi fth edition of Clinical Periodontology and Implant Dentistry began in early 2007, it became clear that we had reached a fork in the road. It has always been my intention that each successive edition of this work should refl ect the state of the art of clinical periodontology and, in doing such, should run the gamut of topics within this subject area.

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  • Deploying fiber to MDUs, such as apartment complexes, condominiums, townhouses, and other multi-family locations, represents a lucrative market for broadband service providers. At the same time, these applications present unique challenges in both greenfield and overbuild scenarios. This paper addresses the key elements of MDU construction practices, including the physical plant from backbone to premise and the architectural decisions required for a successful MDU application. It will also cover additional network considerations for equipment and connectivity techniques....

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  • Whereas U.S. cities have seen dramatic improvements in air quality over the last three decades1, Mexico City has been considerably less successful. Levels of major air pollutants in Mexico City routinely exceed maximum exposure limits established by the World Health Organization (WHO). For example, the WHO has warned that eight-hour average ozone levels exceeding 100 micrograms per cubic meter threaten human health. 2 During the period 1986-2005, this guideline was exceeded in Mexico City for 92% of all days. A large literature documents the social cost of air pollution (e.g.

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  • Each of the case-studies reported on how increased donor support for health has made it difficult for MOHs to successfully argue for additional domestic sources of revenue for the sector – each site experienced this dilemma to varying degrees. The findings of the case-study in Malawi show increases in development assistance to the health sector occurring at the same time as government- wide budget allocations to health were reduced or shifted to other line ministries.

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  • And although the marketing function masquerades under many names within nonprofit organizations— Communications, Advancement, External Affairs, Public Relations, or Brand Management — the primary objectives are pretty much the same: to define and then defend an organization’s position, and move it closer to success in its mission.

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  • This guide leads you through the basics of marketing—covering product, place, price, people, and promotion—that you must think through before even starting your promotion and publicity efforts. Promotion (your flyers, ads, etc.) and publicity (what the media and others print about you) are given special consideration, explaining various techniques and approaches that can be used for successful marketing. We hope you that this guide will help you get your message out efficiently and vto a greater number of people.

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  • Protected areas are considered essential for biodiversity conservation and the main hope we have of halting the extinction of many threatened or endangered species. Since protected areas can also be a significant source of financial benefits their management is complicated and dependent on many external factors. It has been demonstrated that careful economic and social development are preconditions for successful protected area management.

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  • Gender is well recognised as a critical consideration for HIV/AIDS organisations. Since the 1990s, HIV/AIDS policy-makers, donors, non-governmental organisations and transnational corporations have adopted gender mainstreaming as the process for integrating gender into development programmes and institutions. There is an increasing body of literature on the successes and challenges of practicing gender

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  • Thescaleandoperationofthesupplychainofbiomassproductionisinfluencedbygeographic conditions,availabilityandeconomicsoffeedstocksupplyandvolumesofvalueaddedproduct. Energy balance and the environmental impact of the processes and products are essential considerationsinselectingasustainableoption.Thegrowthofbiobasedindustryindeveloping countrieswill require greater investments for both large volume products (e.g. biofuels) and highvalueaddedproducts,suchasbiobasedspecialtychemicalsorconsumergoods.

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