Danio rerio

Mục tiêu của nghiên cứu này là sử dụng cá ngựa vằn (Danio rerio) để đánh giá tác động của Crom (VI) lên quá trình phát triển của cá ngựa vằn ở các giai đoạn khác nhau, bao gồm ở giai đoạn phôi, ấu trùng và cá trưởng thành.

113p khanhchi090625 04-04-2024 14 4   Download

We have determined the nucleotide sequence of a zebrafish cDNAclone that codes for a cellular retinol-binding protein type II (CRBPII). Radiation hybrid mapping revealed that the zebrafish and human CRBPII genes are located in syntenic groups.In situhybridization and emulsion autora-diography localized theCRBPIImRNA to the intestine and the liver of adult zebrafish.

8p research12 23-04-2013 45 4   Download

We have determined the cDNA nucleotide sequence, deduced the amino acid sequence and defined the gene structure for the cellular heart-type (H-FABP) or fatty acid-binding protein 3 (FABP3) from zebrafish. The zebrafish FABP3 exhibited the greatest amino acid sequence identity to fish andmammalian heart-type FABPs. 3¢RACE and 5¢ RLM-RACE mapped two alternative polyadenylation sites and three transcription start sites, respectively.

12p tumor12 20-04-2013 34 2   Download

Thebrain fattyacid-bindingprotein (B-FABP) is involved in brain development and adult neurogenesis. We have deter-mined the sequence of the gene encoding the B-FABP in zebrafish. The zebrafish B-FABP gene spans 2370 bp and contains four exons interruptedby three introns. The coding sequence of zebrafishB-FABP gene is identical to its cDNA sequence and the coding capacity of each exon is the same as that for the human and mouse B-FABP genes. A 1249 bp sequence 5¢ upstream of exon 1 of the zebrafish B-FABP gene was cloned and sequenced. ...

11p tumor12 20-04-2013 53 2   Download

Thebandccrystallins are evolutionarily related families of proteins that make up a large part of the refractive structure of the vertebrate eye lens. Each family has a distinctive gene structure that reflects a history of succes-sive gene duplications. A survey ofc-crystallins expressed in mammal, rep-tile, bird and fish species (particularly in the zebrafish, Danio rerio) has led to the discovery of cN-crystallin, an evolutionary bridge between theband cfamilies.

16p awards 06-04-2013 39 2   Download

Prion diseases are characterized by the accumulation of a pathogenic mis-folded form of a prion protein (PrP) encoded by the Prnpgene in humans. In the present study in zebrafish, two transcripts and the corresponding genes encoding prion proteins, PrP1 and PrP2, related to human PrP have been characterized with a relatively divergent deduced amino acid sequence, but a well preserved overall organization of structural prion pro-tein motifs.

14p awards 05-04-2013 40 2   Download

We have cloned and determined the nucleotide sequence of the cDNAcoding for a cellular retinol-bindingprotein type I (CRBPI)from zebrafish. The deduced amino acid sequence of the zebrafish CRBPI showed highest sequence identity (
59%)to the mammalian CRBPIs of the intracellular lipid-binding protein (iLBP)multigene family. Phylogenetic analysis clustered the zebrafish CRBPI to the CRBPI clade. The zebrafish CRBPI gene (rbp1)and CRBPII gene (rbp2) both consist of four exons separated by three introns, iden-tical to all otheriLBP genes in vertebrates....

10p dell39 03-04-2013 47 4   Download

We previously reported that zebrafishaB-crystallin is not constitutively expressed in nervous or muscular tissue and has reduced chaperone-like activity compared with its human ortholog. Here we characterize the tissue expression pattern and chaperone-like activity of a second zebrafish aB-crystallin.

10p dell39 27-03-2013 37 4   Download

Fatty acid-binding protein type 1 (FABP1), commonly termed liver-type fatty acid-binding protein (L-FABP), is encoded by a single gene in mam-mals. We cloned and sequenced cDNAs for two distinct FABP1s in zebra-fish coded by genes designatedfabp1a andfabp1b. The zebrafish proteins, FABP1a and FABP1b, show highest sequence identity and similarity to the human protein FABP1.

14p inspiron33 25-03-2013 39 2   Download

Teleost fishes differ from mammals in their fat deposition and distribution. The gene for adipocyte-type fatty acid-binding protein (A-FABP or FABP4) has not been identified thus far in fishes. We have determined the cDNA sequence and defined the structure of a fatty acid-binding protein gene (designated fabp4) from the zebrafish genome.

13p galaxyss3 21-03-2013 48 4   Download

We have determined the structure of the fatty acid-binding protein 6 (fabp6) gene and the tissue-specific distribution of its transcripts in embryos, larvae and adult zebrafish (Danio rerio). Like most members of the vertebrate FABPmultigene family, the zebrafishfabp6 gene contains four exons separated by three introns.

10p galaxyss3 07-03-2013 37 4   Download

Genomic and cDNA sequences coding for a fatty acid-binding protein (FABP) in zebrafish were retrieved from DNA sequence databases. The cDNA codes for a protein of 14.7 kDa (pI= 5.94), and the gene consists of four exons, properties characteristic of most vertebrate FABP genes. Phylogenetic analyses using vertebrate FABPs indicated that this protein is most similar to zebrafish Fabp10.

11p viettel02 20-02-2013 36 3   Download

ZF-RNase-3 is one of the RNases from zebrafish (Danio rerio) with special (i.e. noncatalytic) properties. These include angiogenic and bactericidal activities. Given the interest of fish RNases as host-defense effectors, we studied the mechanism of the bactericidal action of ZF-RNase-3 onEscheri-chia coli as a model Gram-negative bacterium.

8p mobifone23 21-01-2013 36 4   Download

Over the past few decades, numerous small molecules have been designed to specifically and selectively target the unusual secondary structure in DNA called the G-quadruplex. Because these ligands have been shown to selectively inhibit the growth of cancer cells, they have become a central focus for the development of novel anticancer agents.

20p mobifone23 18-01-2013 34 6   Download

Protein arginine methyltransferase (PRMT)1 is the predominant type I methyltransferase in mammals. In the present study, we used zebrafish (Danio rerio) as the model system to elucidate PRMT1 expression and function during embryogenesis.

13p cosis54 05-01-2013 27 3   Download

Cá ngựa vằn Danio rerio là loài cá được bán phổ biến trong các cửa hàng cá cảnh và được nhiều người chơi cá cảnh trên toàn thế giới biết đến. Trong nuôi thủy sản hiện đại, dị tật trên xương sống làm giảm giá trị của sản phẩm.

8p thulanh3 08-09-2011 41 2   Download